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Homo sapiens (human) long intergenic non-protein coding RNA 1391 (LINC01391) URS000002F901_9606

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LINC01391: LINC01391, a long non-coding RNA (lncRNA), has been investigated in relation to cell invasion and migration in gastric cancer cell lines [PMC7532492]. Knockdown of LINC01391 was found to significantly accelerate cell invasion and migration in SGC7901 cells, as demonstrated by transwell assay with or without Matrigel (Figure 3A, 3B-D) [PMC7532492]. Conversely, overexpression of LINC01391 was found to significantly repress cell invasion and migration in BGC823 cells (Figure 3E, 3F-3H) [PMC7532492]. Additionally, qRT-PCR assay showed that LINC01391 knockdown led to an elevation in miR-12116 expression in SGC7901 cells (Figure 7D), while LINC01391 overexpression repressed miR-12116 expression in BGC823 cells (Figure 7E) [PMC7532492]. These findings suggest that LINC01391 may play a role in regulating the invasive and migratory capabilities of gastric cancer cells. Further research is needed to elucidate the underlying mechanisms by which LINC01391 exerts its effects on cell invasion and migration [PMC7532492].

Genome locations

Gene Ontology annotations

Sequence

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AACGUCAGCAGAAAGACUUUUUCUGCCGUGGUUCGUUCACAAGGCGCGACUGUAGGCAGAGGCUCCCUGUUCUGAAGCUGGCUGUCAGCACUCCCCCAACUGCCGUCUCAAGCAGAGAAAGCAAGGGAGGGAAGCUUCCAGGACCAAGCCCUGGUGGGCAGGUAGCAGCCCACCUCCAGUGAGACGGAGAAGUUGGCCGGGGCCAGCAAUGAAGGACCAGCCUGUCUCCUCCCCGAGAACUGAAAGGCAAAAGGCACCCAAGGCUGGGAAGAGAGCAGCAGCCUCACCAAACACUUCUGGGUGAUGCGAGUGCUGCGCAGCUCAGAACCCUUGGAAGCAUGAGAGGAGGACGAGCCCGGCGGCCUGCCGGUGCGGUGAUGGAGGGCUCUUCGGUAGCCACACUGCGCGCCUCCCACACACACCUUAACAGUCUUGGGGCCCCGGGCCAGCGCUGCAGCCCAAAGAGACCCUGCAGCCGCAUUUUCUCCCAGGCCGUGGCAAACCCUGGCUUCGCCUCCCUUCACCAUGGCUUGUGAGGGCAGGAGGCUCCCGGGGGCCGACUUCCCUGACCUGAAUGAGUCAGGCACCCUUCUUUAUUUUAAGUGGGGGUGUGACCUGAGGAGAUAAAGGAAGGACGACAGACCUGGGGAGUGGGGCCCUGCAGCCUCUUGGGCCCGGAGCGCACUCCUUCUCGCUCCCUCCCCUCACCGGCAGGAUCGGGGGUCUUGAAACUGGAGCCGCUCACCGGCCGGCGGAUGAGAGAUAAAGGAGCCCGGCGGCGCCGAAGCGCUGACCAGCAGACCCGGAUCCGGACUUUCCCGCGCUCCAGAGCAGCACCCGAAACCCUACUUCCCAGGUGGCACCGACGGCUGAGCAGCUCCUCCGGUGCCAUACGGUGUCUCCAGGCACAGACAGUCGUGCUCGCGUGUGUACUGUGCACGCACAAGACUGCAGGAUGAUGUCCUGUAUGAGCCCUGUAUUAGCCCCUUUGCUCUCAGCCAGAGGUACACGCAUACGUGUGUGCAUUUGUCAAGUGUCUAGGGACAGGUGUGCACCUUCACACAUACGUGAUGUGUAUGUGCACACAUUUGUAGAACGUUCUAGCAUCUAUCCUACAGGCACGUACAGGGCUGGCUGCUUCUAAUAAGUCAUCAUUACACCUCGCAUUUACACAGGCCUUUUCAGUUCUGGCAUGAUUUUCAGAAUCACCCCGGGAAAUACUCUCCUUUCAAAGUUUACAGAUGAGGAAACAAGCAAAAAGAAUCUAAUGGGUACCCGUUUGCACACACUGUGAGAGAGAUCGAGGCCAGCCAAAGAUCCCGCCCACUGUUGAACUUGGGUGUGUUGGCCGAAUGUGCUCAUAGAUGGGUCUGUUUAGCGCCCCAGGCGACCUCAGGUCCGGCGGGCCUUGGCUCUUCGCCAGGCUUCCUGGGAGACCCACUGCGCCGGGUGUGGGGUCUCAAUUCCUGUGCUGAUAAGCACUAUCUUCUGGAGCUGGGUGACCCUAGUGCCCAGGGCGGGAAGUCGGGAGCUGGCCGGAGUGCCGCUGAGGCGAUCCCGGCGGUUCCAAGGCCAUGGCUGACCACGCGCAACUGGGUUGCAAAGCCUGGCGGGCCUCGGUCUCUAAAGCAGCCACGCCAGGCAAACGUGCGAUGAAAGGAUCCUUUCAGCCCACCUACAAACCCAGGAACCCAGGGUUGCUGGAGCAGUGAGGAAAUUCCUGCUGUCUCGAAUCCCUAGCGCCCUUACGAGACUCGGAGCCCACAAUGCCCAUUUUACAGAAGUGAUUAGUCGGAGGCUAGAGCGGUAUAGUGAGUUGCUCAAGUUCAACGCCAGUUGAGUGGCCACAGUCGGGACUGGAAUCCCCAAUUAAGUGUGUCUGGAUCCUUGGUCCACAGUCCCUCUGCCCCCAGCAAGGAUCGCUGGUCCCUCUGUCUCCCGCGCGCCCAGGAGCCAUCCCGCUACUAGCCUCCGACUUCCCUCGCCAAGAAUGCGAAAACUAUCAUAGCUCUCACCAGCAUCAUUUAAAAGGUUUCCACAUGCUUGGAAUCUGUUGCUUGAAAACAAAUUCCCUGUGUGCGUUGGCUUUCUAACCCCUCCUAAGGCAUCUGGUCCCCCUCCACCCUCUAAGCCCUUGCCGUCGCAGAGUGAGGCUGCCUAAGGGCUGUAGCUUGACCACAUCCCGGGGGUGCCCUUGGGCCUCUGCGCCGGGCUCCUGCAGACUGAGGUCGCUGGUCUCUGGGCUCCAAGGCCGCCUCUACCCCGCAGAAUCCGGGAGCUGGAAGGGAGCCCGCGGUUUGGCGAGGUCGCCGUUCGGGCUCACGGCCUCGAGGCUGCCCUCUGCUGGCACUGGGCGACAUUACCACCGCCUCCCUCGGCGGCUCAGGAGCUGCACCCACGUGAGGGGUUCGCGCAGAGCCAGGCGACCCCAUUCUCACUGGGUCCCCAGAGUGGCUGCCGCACCUGCAGCCACUGACGAGACCCUCCCGUAUUUCUCAAUCCGAGACUUCUCCCCGCAGACACCAGAGGCUCCGGUGCUCGGACCCAGGGACAAGGCAGAGAGCCGGAGCUCUGCGCUGGCAAUCCCGCCGCUUUGCGGCGCCCGCCGGGAUCCGCGGCCAACCAGGCACGGCCACAGGCGGACGCUGGGGGACUCCGGGGAUGGCCCCAGGCUGUGUUCGUCCCCUUUACUCUCCGCCACCAUAGCAUUGAUUGGCGCCCACGGGUCCCGAUCUACCUGCCCUCCCCUUUUCAACCUUACUUGAUGGUGGCCCAGGCGCUUGGCUGCCUCUGUUUCUUGUAGUGCACUUGUCUCUCCAACCAAAUUAAGAGCGCCUCGACGACCGGAAGGGGCUGCUCCCUACCCGCACGGCACAGGCCUAGCUCAGGUUCUGCCGAGACAGAACUGAUUCCAGAGGCCCCCAUUCUUGCCCUUGAAAUAAACUUUAGGCAGUGAGGCGAAGAGACACUUCUGCCUGCUGCAUCCAUUCUAGACAGGGUGGGGUAAAAAUUACUCAGUCAUCAUAUCUAUGCAUUUCCAGUGCUAUGUAUUAGGACUUUAACAUUUUCACUUUUCCCCUCACAAAGAUAAUUGAAACUGAAGAAAAUUGGGAAAAUAAAACAUUAAAAUGCACAAAAAACACCAACGCGACAAUAAUCCCAUCCCUCCUCCCACAAGGUAACCAUGGUUAACAUUUCGAUGGCAUCUUUCCAGUCUUUUAUUUAUAUAUUUCAAUUAAAAUAAGCCUAAUUUCCAUAAUUAACAAAUAUACAUAAAAUUUGCAGUUUUGUAUCCUGCUUGUUUAAACCUUUCGCCAUAGGGUUUUUCUCCAUAUCUUAUUCUUUGAAAAAUGAUUUUCAAUUAUUGCUUAAUAAUCCAUCCUUUGGAUGAACCAUAAUUUUGUUAUACACCAGCACCAAUUAUCUGUUUUAGGCCCAGGAAAGUCUCCUUAAGCCACACUCUCUGGAUCCGUCUGGAUCAGUUAAUAUAUAAUCAUAUAAUCAGUAGUUGAUCAAUAAAUGUUGAGCCUUUCUUUUU

Taxonomic tree

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Expression New Publications