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Homo sapiens (human) mitochondrially encoded tRNA-Pro (CCN) (MT-TP) secondary structure diagram

Homo sapiens (human) mitochondrially encoded tRNA-Pro (CCN) (MT-TP) URS000002176F_9606

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MT-TP: MT-TP is a tRNA gene that shows the presence of variants [PMC8365099]. In the non-obese group, five SNPs were detected, including MT:10499A > G, MT:10609T > C, MT:3197T > C, MT:16288T > C, and MT:16359T > C [PMC7920096]. The m.15992A>T mutation in the MT-TP gene was found in all patients [PMC7371370]. In a study comparing gene trees and sequence data analysis, MT-TP (tRNA-Pro) was found to cluster Pteronura brasiliensis with non-otters [PMC3307490]. In Caco-2 cells infected with Salmonella, RNA coding components of the mitochondrial respiratory chain including MT-TP were highly elevated compared to uninfected cells [PMC10076011]. Among 22 mt-tRNAs, eight (MT-TE, MT-TA, MT-TN, MT-TC, MT-TY, MT-TS1, MT-TQ and MT-TP) occur at the L-strand while the rest are present in the H-strand [PMC9657367].

Genome locations

Gene Ontology annotations

Sequence

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CAGAGAAUAGUUUAAAUUAGAAUCUUAGCUUUGGGUGCUAAUGGUGGAGUUAAAGACUUUUUCUCUGA

Taxonomic tree

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This sequence is found in 3 other species

  1. Homo heidelbergensis (Heidelberg man) tRNA-Pro
  2. Homo sapiens neanderthalensis tRNA-Pro
  3. Homo sapiens subsp. 'Denisova' transfer RNA-Pro
2D structure Publications