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hsa-miR-320d: Hsa-mir-320d is a downregulated microRNA that has been identified in a study as having a fold change of -4.57 [PMC7488025]. It is part of a plasma exosomal miRNA profile that includes Hsa-miR-320c and Hsa-miR-320b [PMC9955173]. This profile has been identified as a potential predictor of efficacy for anti-PD-1 treatment [PMC9955173]. The study also found other upregulated microRNAs, including hsa-miR-2355-5p, hsa-miR-149-5p, and hsa-miR-582-5p, with fold changes of 39.81, 29.22, and 23.15 respectively [PMC7488025]. Additionally, other downregulated microRNAs were observed such as hsa-miR-362-5p and hsa-miR29b3p with fold changes of 45.35 and 24.62 respectively [PMC7488025]. These findings suggest that hsa-mir320d and the other identified microRNAs may play important roles in the efficacy of anti-PD1 treatment [PMC9955173]. Further research is needed to fully understand the mechanisms by which these microRNAs influence treatment outcomes and to explore their potential as biomarkers for predicting response to anti-PD1 therapy.
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