v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) long intergenic non-protein coding RNA 1569 (LINC01569) URS000000B904_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LINC01569: LINC01569, a long non-coding RNA, has been implicated as a potential carcinogen through its interaction with miR-381-3p [PMC8378226]. Research has shown a significant increase in the expression of LINC01569 in patients with colorectal cancer (CRC) [PMC8378226]. The role of LINC01569 in the regulation of mechanosensors and its potential binding to the glucocorticoid receptor (GR) has also been investigated [PMC7904261]. Previous studies have demonstrated that LINC01569 can mediate glucocorticoid effects on mechanotransduction by destabilizing messenger RNA (mRNA) of mechanosensors [PMC8378226]. LINC01569 is a long non-coding RNA that has been implicated in cancer development and progression. It is suggested that LINC01569 may act as a carcinogen by sponging miR-381-3p, thereby affecting downstream signaling pathways [PMC8378226]. In this particular study, the expression of LINC01569 was found to be significantly increased in patients with CRC, indicating its potential role as a biomarker for this disease [PMC8378226]. Furthermore, the researchers investigated whether LINC01569 could mediate glucocorticoid-induced effects on mechanosensors. It was hypothesized that LINC01569 may regulate or bind to the GR to modulate gene expression and downstream signaling pathways involved in mechanotransduction [PMC7904261]. Previous studies have also shown that LINC01569 can destabilize mRNA of mechanosensors, thereby affecting their expression and function. This suggests that LINC01569 may play a role in modulating cellular responses to mechanical stimuli through its interaction with mRNA molecules involved in mechanotransduction pathways [PMC8378226].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
GGACUCCUUCAGCGCGCUGCCUGCCUGCCCAGGGCCUUCCCGGAGAGCAGGUGACGGCGGCCUCCGGGCAUGGAGCUCGCGCUGACGAAAGGUUCUGGAAGCCGCCGUAAAAAGUAAUCAAGAAACGGGUGACAGGACUUUUCGAACAAGGUCUCACCAUGCUGCCCAAGCUGGUCUGAAAACUCUUGUCCUCAGGCAGUCCUCCCACCUCGGCCUCCCAAAGAUCUGAGAUUACAGGCAUGAGCCACCACACCUGGCCUUGGUUUUAAUUCCUGUCACAGUAUAUUAGUUUUCGCUGUUGUGUAUUGAUUGAUUGAGACAGGGUCUCGCUCUGUUGCCCAGGCUGGAGUGCAGGGGCAUGAUCCCAGCUCACUGCAACCUCCACCUCUUGGAUUCAAGUGAUUCUCCCGUCUCAGCCUCCCGAGUAACAGGAACCACAGGUGUGUGCCAGCACGCCUGGCUAAUUUUUUUUUUUUUUUUCUUGAGGUGGAGUUUCACUGUUGUUGCCCAGGUUGGAGUGCAGUGGCACAAUCUCAGCUCACUGCAACCUCUGCCUCCUGGGUUCAAGUGAUUCUCCUGCUUCAGCCUCACGAGUUGUUGGGAUUACAGGCGCCCGCCACCACGCCCAGGUAAUUUUUGUUUAGUAGAGACGGGGUUUCACCAUGUUGGCCUGGCUGGUCUCGAACUCCUGACCUCAGGUGAUCCACCCACCUCGGCCUCCCAAAGUUGUGGGAUUGCAGGCGUGAGCCACUGCGCCUGGCCUAAUUUUUCAAUUUUUUGGUGGAGAUAGGGUUUCACCAUGUUGGCCAGGCUGGAGUUUUGCCUGUUCUAGAAGCUUGUAUCAGUCAUACAACACCCCUUUGAGGAACCGUUUGAGGUGUGGCACGAUACAGCAAGUCAGCUGCCAAAGAGGGGCUUAGCCACAGGAAGUGCGUGCCCAGAACGGUAAAGGGGCUGUGGCCUUUCUUAUCAUCUCCACUCCCUGUCCCCCCCAUCACCUGCUCUUCGUGCUUUGUGAUAAUUCAGUGAGCUCAUACUCAUGACCUGUGUCCUCCAGCAUCUCCCGUGUCCCUCACAGCAGUUCUAUGAGGCUGGCUGCCCUGUUUGACAACUGAGGCCCGCAUCUUCCCCGGAAUCACCGACGUGUGGCUCUGAGCCCUGUCCCAGGGAUUUUCUCCAUCAGAGAAGAGGAGCACUUUGAGCUUUGAGAGGAGCAGCCCUCUGCAAGUGAAGUGGAAAAAAAGGAAGCAGGCGAGGAGGCCCAUCCAGACCCUCCCCCAAGACCCUUGCUGAAAUGGCUGGGAUGCGGCGUGCAGAAGCUCUCCUUUCCUUCACAGCCCCUGGCUUUCCAAGAGUCCCUGCCCACCCAGAUGCCCGCUGGCAGAUGCAGCCUCAUCUCAAGGACACUGCUUGCUGGAUAAAUCCCUCACCACCCUAGAGACAGCCCACGGUCCUGAGACAAGGAUGCGGGCCAGGCUUGUUGCACGUAAGCGCCUCCCGCAGAAACCAGUGAGGCCGGAGUUCCAGAGGAAAUGAUGUAGGGACAGAGGCAGAGGGCCUCCAGGAGGCACCAGCCCCAGAGUCUUCCCUAGAAUCAGACUUUAAGCACAAGCAGGGAGGGAAAGCACUUGAGCAGUGCCCGUCCCUGCAUACCUGGCCUCUGCUGGAACCCAUGCAGGGACAGGACACUUCUUUAUCAGCAAUCCUGUUCCUCUCCUGGGCAGCUUCAACCUGAACAUCCUCCUUCACCUUGAGCUAAAAUGGGUUUCUUGUCACCCUUGCCCAUCAAACCUGGCCUUGCCCUCAGGAACCACACAGGACAAGCCUAAUACUUCCUUCUUGUGGCAACACUUUAGCAAUUGAGACCUGGCUGUCAGGUCCUCCAAAUAAACAUUUGUGACUGUGAUGUUGACUUGCCGCUUCUGGGGACCUCUUCUCAUUUGAUCGGAGAAAGUUUUUCAGGGUUAAACCUACUUCUUUCCCCCAAGAAACUCUUCUUGUCAGGCUCACGCCUAUAAUCCUGGCACUUUGGGAGGCCAAGGCAGGAGGAUUGUUUGAGACCAGCCUGGGCAACGUAGGUAGACUAUGUUGCU

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications