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Homo sapiens (human) hsa-miR-340-5p URS0000007FBA_9606

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hsa-mir-340: Hsa-mir-340 is a microRNA that has been found to be downregulated in the low bone mineral density (BMD) group and is correlated with the expression level of its target gene PDPK1 [PMC4577125]. In prostate cancer cell lysates, hsa-mir-340 was used in a DNA pull-down assay to target and bind with streptavidin-containing magnetic beads [PMC7884413]. However, the reduced expression of hsa-mir-340 did not significantly improve cisplatin cytotoxicity, while increased expression of hsa-miR-302b enhanced cisplatin cytotoxicity [PMC3590172]. In dilated cardiomyopathy (DCM) samples, hsa-mir-340 was found to be significantly differentially regulated compared to non-failing control samples [PMC4118176]. Additionally, hsa-mir-340 was found to be upregulated in DCM samples along with other miRNAs such as hsa-miR-19b and hsa-miR-302 [PMC4118176]. Higher expression of hsa-mir-340 was associated with shorter overall survival time in endometrial cancer patients [PMC9200351]. In the context of COVID-19 interaction, hsa-mir-340 was among the significant miRNAs identified in the TF–miRNA network analysis [PMC9429819]. Hsa-mir-340 has also been associated with mitochondria in HEK293 cells along with other miRNAs such as hsa-miR-25 and hsa-miR-423-5p [PMC3439422]. Complementary sequences were detected between COMMD6 and hsa-mir-340 as well as between lncRNA TEX41 and hsa-mir 340 [PMC6889128][PMC6889128].

Genome locations

Gene Ontology annotations



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This sequence is found in 24 other species

  1. Bos taurus Bta-Mir-340_5p (mature (guide))
  2. Callithrix jacchus cja-miR-340
  3. Canis lupus familiaris (dog) cfa-miR-340
  4. Capra hircus (goat) chi-miR-340-5p
  5. Cavia porcellus cpo-miR-340-5p
  6. Cervus elaphus cel-miR-340
  7. Cricetulus griseus (Chinese hamster) cgr-miR-340-5p
  8. Dasypus novemcinctus (nine-banded armadillo) dno-miR-340-5p
  9. Daubentonia madagascariensis dma-miR-340
  10. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-340_5p (mature (guide))
  11. Equus caballus eca-miR-340-5p
  12. Macaca mulatta mml-miR-340-5p
  13. Microcebus murinus mmr-miR-340
  14. Mus musculus (house mouse) mmu-miR-340-5p
  15. Nomascus leucogenys nle-miR-340
  16. Oryctolagus cuniculus (rabbit) ocu-miR-340-5p
  17. Otolemur garnettii (small-eared galago) oga-miR-340
  18. Pan paniscus ppa-miR-340
  19. Pan troglodytes ptr-miR-340
  20. Papio hamadryas (hamadryas baboon) pha-miR-340
  21. Pongo pygmaeus (Bornean orangutan) ppy-miR-340
  22. Pteropus alecto pal-miR-340-5p
  23. Rattus norvegicus rno-miR-340-5p
  24. Sus scrofa (pig) ssc-miR-340