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MIR320A: MIR320A is a microRNA that has been studied in various contexts. In one study, a sponge320a expressing vector was transfected into HeLa cells to reduce the levels of endogenous MIR320A, allowing the researchers to test a hypothesis [PMC5363649]. Another study analyzed the effect of different doses of UVC radiations on HeLa cells that had been stably silenced for MIR320A, in order to assess its relevance to the DNA damage response [PMC5363649]. MIR320A has also been identified as a sensitive and specific diagnostic marker for myocardial infarction, along with miR49922 [PMC7123062]. In hepatocellular carcinoma cells, Vps4A was found to selectively encapsulate oncogenic miR-27b-3p and miR-92a-3p into exosomes and secrete them out of cells, while accumulating oncogenic miR-193a-3p, MIR320A, and miR-132-3p within the cells [PMC9240252]. The relative quantification of various microRNAs including MIR320A validated the results obtained from Illumina sequencing in another study [PMC4486185].
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