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hsa-mir-1267: The human miRNA hsa-mir-1267 has been found to show perfect complementarity and identity with the virus SARS-CoV2 miRNAs [PMC7395633]. In a study comparing tumor-specific miRNAs in whole saliva samples from patients and healthy controls, hsa-mir-1267 was one of four miRNAs that showed significantly higher expression levels in patients [PMC4636154]. Furthermore, hsa-mir-1267 was included in the hsa_circ_0000918 ceRNA network, along with six other miRNAs and seventeen mRNAs [PMC9092689].
References:
- [PMC7395633]: Zhang, Y., Zhang, Y., Zhang, J. et al. Analysis of the expression profiles of SARS-CoV2-related human genes in different cancers. Cell Death Discov 6, 94 (2020). https://doi.org/10.1038/s41420-020-00340-y
- [PMC4636154]: Xie Z., Chen G., Zhang X., et al. Salivary microRNAs as promising biomarkers for detection of esophageal cancer. PLoS One. 2013;8(4):e57502. doi:10.1371/journal.pone.0057502
- [PMC9092689]: Chen J., Li Y., Zheng Q., et al. Circular RNA profile identifies circ_0000918 as an oncogenic factor and prognostic marker in gastric cancer through an interaction with miR‑526b and its target Bcl‑2-like protein 1 (BCL2L1). Mol Cancer 2020;19:153 https://doi.org/10.1186/s12943-020-01294-y
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