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SNORD65: SNORD65 is a small nucleolar RNA (snoRNA) that has been found to be involved in various biological processes. It has been shown that immune-activating or inhibiting stimuli applied to primary DCs can increase the levels of SNORD65 within extracellular vesicles (EVs) [PMC10050728]. However, SNORD65 is not considered a stable reference gene for miRNA normalization [PMC6883285]. In certain conditions, such as in scERĪ±KO satellite cells and hepatocellular carcinoma, the expression of SNORD65 is dysregulated [PMC6655560] [PMC9818347]. SNORD65 has also been reported to be upregulated in relapsed BCP-ALL patients compared to patients without relapse [PMC9413531]. Additionally, SNORD65 has been found to be associated with certain molecular panels and coping behavior in different contexts [PMC8417057] [PMC7461500]. It is worth noting that the expression levels of SNORD65 can be normalized using other small noncoding RNAs such as Rnu6, Snord68, Snord87, and Rny1 for more stable reference gene normalization [PMC3184962]. Overall, these findings highlight the diverse roles and dysregulation of SNORD65 in various biological processes and diseases.
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