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hsa-mir-578: Hsa-mir-578 is a microRNA that has been implicated in various biological processes and diseases [PMC8173208]. It has been found to be differentially expressed in gestational diabetes mellitus (GDM), suggesting its potential role in this condition [PMC8173208]. Hsa-mir-578 has also been identified as a potential binding partner for circ_0006677, indicating its involvement in circRNA-miRNA interactions [PMC8155686]. In addition, hsa-mir-578 has been shown to be upregulated in combined analyses of GSE46823 and GSE83292 datasets, along with other miRNAs [PMC9812810]. It has been found to modulate the expression of SHOX2, CTNNB1, and EGFR mRNAs through a coexpression network [PMC9260928]. Hsa-mir-578 has also been implicated in the regulation of XPNPEP1, UCHL1, DBNL, GPC6, and RAD51 expression or activity through sponging specific miRNAs [PMC9627163]. Furthermore, hsa-mir-578 has been shown to regulate the expression of HIF1A, VEGFA, ANGPT2, and FAK genes in different cell types [PMC4381608]. It is also known to interact with other miRNAs such as hsa-miR-140-3P and hsa-miR-145-5p [PMC7595675][PMC8324362].
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