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Homo sapiens (human) small nucleolar RNA, C/D box 89 (SNORD89) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, C/D box 89 (SNORD89) URS0000633321_9606

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SNORD89: SNORD89, a small nucleolar RNA (snoRNA), has been implicated in the regulation of the Notch pathway in ovarian cancer [PMC6686521]. In a study using Ishikawa cells, plasmids overexpressing SNORD89 were transfected, suggesting a potential role of SNORD89 in ovarian cancer [PMC9256700]. Additionally, Kaplan-Meier analysis identified SNORD89 as one of four snoRNAs associated with poor prognosis in ovarian cancer [PMC6686521]. The expression of SNORD89 was further confirmed in clinical samples [PMC9256700]. In the context of endometrial cancer, analysis from the TCGA database revealed significantly increased expression of SNORD89 in endometrial cancer tissues compared to normal endometrial tissues [PMC9256700].

Genome locations

Gene Ontology annotations

Sequence

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ACUGAGGAAUGAUGACAAGAAAAGGCCGAAUUGCAGUGUCUCCAUCAGCAGUUUGCUCUCCAUGGGCACACGAUGACAAAAUAUCCUGAAGCGAACCACUAGUCUGACCUCAGU

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2D structure Publications