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hsa-mir-3149: Hsa-mir-3149 is a microRNA that has been implicated in various biological processes and diseases. It has been reported to play a role in tumorigenesis, DNA repair, and immunity [PMC7851581]. In osteosarcoma, the downregulation of hsa-mir-3149 has been shown to promote cell proliferation and metastasis [PMC7851581]. In addition, hsa-mir-3149 has been found to inhibit the expression of ovarian tumor protease deubiquitinase 5 (OTUD5), suggesting its involvement in DNA repair and immunity [PMC7851581]. Hsa-mir-3149 has also been associated with glaucoma, with lower expression levels observed in glaucoma patients compared to controls [PMC8237107]. Furthermore, hsa-mir-3149 is among the miRNAs that are differentially expressed in gastric carcinoma compared to normal gastric cells [PMC6584754]. It is worth noting that hsa-mir-3149 is also associated with poor overall survival in cervical squamous cell carcinoma (CESC) patients [PMC7333649]. These findings highlight the potential role of hsa-mir-3149 as a biomarker and therapeutic target for various diseases.
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