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bta-mir-140: Bta-mir-140 is a miRNA that has been detected in various studies and is part of the top 10 most abundantly expressed miRNA families in bovine species [PMC5003961]. It has been found to be expressed across the bovine estrous cycle without differences among the stages [PMC7969882]. In one study, bta-mir-140 was found to be up-regulated in OF-sEV/Pregnant and down-regulated in OF-sEV/Non-pregnant groups [PMC7969882]. Another study found that bta-mir-140 had a higher number of copies during the spring compared to summer and fall [PMC4990326]. It was also upregulated in older animals and fetal muscle tissue [PMC4990326]. In the context of embryo development, bta-mir-140 was downregulated in EVs secreted by arrested embryos but upregulated in EVs from competent embryos [PMC7727673]. Additionally, bta-mir-140 was found to be regulated both in skeletal muscle and mammary tissue [PMC5325256]. It is one of the known miRNAs with a broad range of expression, with thousands of sequence reads for the most abundant miRNAs such as bta-mir-21 and bta-mir-140 [PMC2713767]. Finally, bta-mir-140 has been detected with different abundance levels among cows at embryo transfer [PMC5662615]. Overall, these studies highlight the presence and potential regulatory role of bta-mir-140 across different biological processes.
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Gene Ontology annotations
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