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osa-miR167d-5p: Osa-mir167d-5p is a miRNA that has been found to be differentially expressed in fungal-infected resistant genotypes of rice [PMC7662745]. It is one of the miRNAs that showed preferential expression in these genotypes [PMC7662745]. Additionally, osa-mir167d-5p was found to be up-regulated by >6-fold in miRNA sequencing results [PMC6042804]. The expression of osa-mir167d-5p was also verified through qRT-PCR experiments, which showed consistent results with the sequencing data [PMC7037501]. It has been reported that rice dwarf virus (RDV) and rice stripe virus (RSV) can induce the accumulation of osa-mir167d-5p [PMC7037501]. Furthermore, osa-mir167d-5p has been shown to be involved in rice immunity response and may play a role in regulating susceptibility to Xoo infection by suppressing the expression of its target gene, OsWD40-174 [PMC7037501]. The regulatory mechanism and role of osa-mir167d-5p in rice immunity response are still not fully understood and require further investigation [PMC7037501]. Overall, multiple miRNAs/targets regulatory units are responsive to Xoo infection, and osa-miR164a, osa-mir167d-5p, and osa-miR159b have been confirmed to have defensive roles against Xoo attack [PMC7037501].
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