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bta-let-7f: Bta-let-7f is a member of the let-7 family of microRNAs [PMC4438052]. It is one of the three isoforms of the let-7 family found in preovulatory dominant and subordinate follicles [PMC4438052]. Bta-let-7f, along with other miRNAs such as bta-miR-196b and bta-miR-33a/b, is involved in regulating glycerophospholipid metabolism by inhibiting the expression of enzymes involved in triglyceride synthesis and degradation [PMC5341059] [PMC6637853]. Bta-let-7f has also been found to be correlated with certain bacterial groups such as Papillibacter and ruminantium [PMC9378797]. In Holstein cattle, bta-let-7f is one of the most abundant miRNAs [PMC5410099]. It is also highly expressed in Angus, Charolais, and KC animals [PMC7653039]. Bta-let-7f is among the top 15 most abundant expressed miRNAs across different regions [PMC7959717]. The abundance of the bta-let-7 family varies significantly in deep sequencing results [PMC3164151]. It should be noted that bta-let-7f and bta-let-7a-5p likely target the same genes due to their belonging to the same family with identical seed sequences [PMC5804041].
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