ssc-mir-143: Ssc-mir-143 is a microRNA that has been found to have increased expression in E. coli F18-sensitive pigs [PMC3427155]. It is one of 12 miRNAs that showed differential expression in pigs susceptible to E. coli F18 infection [PMC3427155]. Ssc-mir-143 has the highest level of expression in the intestinal tract and is believed to be related to a rapid growth phase in weaned piglets [PMC3427155]. It has also been associated with fat metabolism and fat cell differentiation in mammals [PMC3427155]. Ssc-mir-143 is highly expressed in pig backfat tissue and represents 20% of the total miRNA expression [PMC3901342]. In addition, ssc-mir-143 has been found to be regulated by three different transcription factors and may play a role in muscle fiber regulation through the HDAC4-MEF2 pathway [PMC3427155] [PMC4410957]. Abundant miRNAs, including ssc-mir-143, have also been found to have higher editing probability [PMC6677090]. Overall, ssc-mir-143 appears to be involved in various biological processes and may serve as a potential disease marker or therapeutic target.