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ssc-let-7i: Ssc-let-7i is a type of microRNA that is abundantly expressed in Laiwu pigs compared to Large White pigs [PMC9859024]. It is one of the differentially expressed miRNAs responsible for regulating subcutaneous adipogenic differentiation [PMC9859024]. In a study comparing PRRSV-infected and mock-infected PAMs, the let-7 family, including ssc-let-7i, was found to be significantly differentially expressed [PMC9550049]. Ssc-let-7i is a 21 nt sequence that lacks three nucleotides (GUU) at the 3' end according to miRBase [PMC4400304]. However, there is some dispute regarding the exact sequence of ssc-let-7i, with some studies suggesting it may be 22 nt in length [PMC4400304]. Ssc-let-7i was found to be one of the most abundant miRNAs in porcine testes and was consistently expressed in all six libraries studied [PMC4400304] [PMC6354428]. In Landraces' lungs, ssc-let-7i was one of six DEmiRNAs that had a high expression value at 0 dpi but were significantly down-regulated at later time points [PMC5381705].
References:
[PMC9859024] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859024/
[PMC9550049] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550049/
[PMC4400304] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400304/
[PM6354428] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM6354428/
[PM5381705] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM5381705/
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