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MT-TH: MT-TH is a mitochondrial tRNA that is present in the H-strand [PMC9657367]. Cleavage at MT-TH occurs rapidly, as indicated by the absence of intermediate processing products in wild-type mitochondria [PMC5435911]. In a study investigating gene expression in different tissues, MT-TH was found to be differentially expressed [PMC9028063]. In grade 3, downregulation of mitochondrial-related transcripts including MT-TH was observed, and these gene expressions were not reported in HD [PMC9777612]. In a study of neonates in the Chongqing area, common mutations were found in genes including MT-TH [PMC8084083].
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