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Homo sapiens (human) long intergenic non-protein coding RNA 1504 (LINC01504) URS0000183E3A_9606

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LINC01504: LINC01504 is a long non-coding RNA (lncRNA) that has been studied in various contexts [PMC6395377]. It has been shown that metformin treatment reduces the expression of lncRNA SNHG7, but not LINC01504, in a dose- and time-dependent manner [PMC6395377]. In the context of rheumatoid arthritis (RA), LINC01504 is downregulated in the RA group compared to the control group, and its expression is negatively correlated with rheumatoid factor (RF) [PMC7792483]. Additionally, LINC01504 has been identified as a validated risk lincRNA in RA [PMC7792483] [PMC6900396]. In non-small cell lung cancer (NSCLC), increased levels of LINC01504 have been observed and are associated with the upregulation of cytokine signaling 1 (SOCS1), BTG anti-proliferation factor 2 (BTG2), and Bruton tyrosine kinase (BTK) [PMC9738375]. LINC01504 has also been implicated as a potential suppressor in NSCLC development [PMC7900626]. Furthermore, LINC01504 is involved in nontranslocation-related sarcomas [PMC7900626]. In the context of asthma, LINC01504 is differentially expressed between T2 asthma patients and healthy controls or non-T2 asthma patients [PMC9035528]. Overall, these studies highlight the potential roles of LINC01504 in various diseases and suggest its importance as a biomarker or therapeutic target.

Genome locations

Gene Ontology annotations

Sequence

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GAAAUGCUGCAGAGACCCAGCCGGAAACAGUGCUGGCCAGCUCACGCCUGACCCACCCUUAUUCUAAGCAUAGGGUCUGCCUCUGAAGAGCUAAAGACUUCCUGAAAUUUAAAAAUUAGUGCUUUUAUUUGCUUGUCCUGCUAAGACCGUAGGCAAAGGCCAUCCUCCUCCCAUUGACAGUUUAGAGUGGGCAGAAACAACCACGGUUACCCUAGAAGUAAAUCCAGAGCUGCGGGACGCUGGAGGACAAAACCAACCUUCCAGGGAAGCCGAGGAGAAGUCAUGCCUUCAAAAGAUGAAGAAACUGACAUCUGGAGAAGUUGAAGUAAUUUGCACAAAGAUUCACUUGGCUAACGGAGUUUUGCUCUGUCACCCAGGCUGGAGUGCAAUGGCCCGAUCUCGCCUCACUGCAACCUCCACCUCCCGAGUUCAAGAGAUUCUCCUGCCUCAGCCUCCCAGGGGCUGGGAAGUUCAAGAUCCAGGCCUCAGAAGAUUUGGGGUUUGGUGAGGGCCAUCUUCUCACUGUAGCCUUACAUGGUGGAAGAGGUAAGGCAGCUCUCUGGAACCUCUUUUAUAAGGGCACUAAUCCCUUUCAUGAGAACUCAGCCCUUAUGAACUCAUCGCCUCCUAAAUUCUCUACCUCCUAACACCAUCACUUUGACAAUCAGAUUUCAACAUAUGAAUUUGUGGGAGUCACCAGCAUUGAGACUAUAGCAACCCCUUAUUAGAAAUAAUUCAUGAGGAACUGAAACUGUUAGGAAACCACUGUGUAAAUGCUGGGAAACAAAGUCAGAUAAAUAAUGCUGAUAAUUACCUGACUGCUUUUGGAACUGUCCUUUUUUGUGAACAUGAGACUACAUCAUUGUCAGUUGAUUGCAGAAGAACCACUAUGAUAUUAUAAUGGGGUCCUGACUCCAUGACUGUGUAAUUCAUGGCUUUCUAACGGUUUAUUAUUGACCUAACUUUGCAGCUCCCCUAGAUCCCCUAACUCCACCAUCUUGGGUUGCAACCAAUGACCUGUUAUUGCAAAACAGGUAAUCUCACUUAGAUAAGUAUUAAUCAGAGGGGCUUGACUUCCAGAGUUCAUUUCAAUGGUUUUCAACUCAUUUGUAGAGUUUAACAUCAGUAGCCCUUUCUCUUCCAUAGGAGGGAGAUGAACCAUCCUGUUUGUUCAAUAAUCAGUGAGAGCGUGGCUUUAACGUCUCUUCCACUCCUUUCUAGUUCAGGUCUUUCUUAACUUGAUGGAGAUAGCUUGGGCCAGGGAGGGCAGAGUGAAGAUGAGAUGGCAAAAAAAAAAAAGUUUUGAUCAGCAGCAUUGACUCUGUGCUAAAUACUGUGCUCAGCUCUUUGGAUGUUAUUUCAUUGAAAUGGAAAGAACACUGUAAAGUUGUCUUGUGAGGCACACUUUCCUGUUGAGGAAAUAAAAGCAUUAAAUAACUUGCCCCCAAAUACAAAGCUAUUAGGAUUGAAACAAAGACUUGAGCCCGGGAUCUAUCUAAUUUCAAGGUCCUUGUUUUUUUUCUACUACAUUUCUCUUUGAGAUACAGUUACUCAAAGGUGUCCAAACUUCAGUUAAUGUCAACCUCUGCCUCACUCUGGUCCUGGUGCCUUUCCCAUGUUCCUGAGAAGAUCAUGUGGCACACUUCUCUAAACGUCUCUGUGCCAUAUCUCUUGGGAUCAAAAGGCCAUUCCAAUAAUUCUUCUGCAUUUCUUAAUGUAUGCUCAGAUGGCCCUGGUUUGCAUUUAGAGAAAGGAAGCUAAGACCUUGGUGAUAACUAAAUAUUUAUAUCUAUUUUUUGAUUAUGUGCUUGUAUUUAAUUAAGUGGGUGCCUACUGUUGUGAAAAUACUUUUGAAUACAAUUCUGAAGUUGUGCCAGGGAACUCUGACAAUGGGUAUGCUGGGAGCUGUCUGAUUUCCUUGUCCUAGACAACUCAUACAAUGCAGUAGAAAAAGAAUUCUUUAUUCCCACUGCCUUUCCUUAGCCCUUCUUCAGAGCAGGGGAAGUGUGACUGUAGCUUUAAAUAGUUUAAAUAGUCCUUCAAAUACGGCAAAUAAAACAGUAUCAAUGAAAAAGAAG

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Expression New Publications