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chi-mir-1343: Chi-mir-1343 is a microRNA that has been predicted to bind to 88 mRNAs in the 30 vs. 18 M comparison and 83 mRNAs in the 18 vs. 6 M comparison, indicating its multifaceted regulatory role [PMC9672515]. Among the differentially expressed microRNAs (DE miRNA), chi-mir-1343 is found to target the most mRNAs (118), followed by oar-miR-370-3p_R-2, bta-miR-2387_R+1, and oan-miR-103-3p_R+2 [PMC9672515]. Furthermore, chi-mir-1343 has been observed to bind to multiple mRNAs in different groups [PMC9672515]. This suggests that chi-mir-1343 may have a crucial regulatory role in sheep tail fat growth and development, although its mechanism in metabolic regulation requires further investigation [PMC9672515].
In addition to its role in mRNA regulation, chi-mir-1343 is also involved in circRNA–miRNA networks. In the HF vs. LF comparison, chi_circ_0030920 targeted by chi-miR-129-3p and chi_circ_0043017 targeted by chi-miR324–3p were identified [PMC8820483]. In the HL vs. LL comparison, circRNAs targeted by different miRNAs were identified: chi_circ_0008353 targeted by chi-miR15a–3p, chi_circ_0041580 targeted by chimiR188–3p, and chici_rc_0016478 targeted by chimi_r134–1 [PMC8820483].
Furthermore, target gene regulatory networks have shown that chi_mir_134 targets a total of 284 mRNAs, which is the highest among the differentially expressed microRNAs [PMC8470123]. These findings highlight the importance of chi-mir-1343 in regulating gene expression and suggest its potential role in various biological processes.
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Gene Ontology annotations
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Sequence
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