MNX1-AS2: MNX1-AS2 is a long non-coding RNA (lncRNA) that is associated with the MNX1 gene on the chromosomal locus 7q36.3 [PMC9688723]. It has been found to be about 2.3 kbp long [PMC10152875]. MNX1-AS2 has been shown to be upregulated in the majority of cancers, particularly in adenocarcinomas and seminomas, compared to squamous and non-seminoma tumors [PMC9688723]. It has been suggested that MNX1-AS2 may have diagnostic and prognostic potential in cancer [PMC9688723]. In particular, high expression of MNX1-AS2 has been associated with poor clinical outcomes in various cancers [PMC9688723]. MNX1-AS2 expression has also shown a strong discrimination of disease subtype, such as adenocarcinomas vs. squamous tumors or seminoma vs. non-seminoma tumors [PMC9688723]. The functions and activity of MNX1-AS2 in cancer are still not well understood, as there are limited reports on its role [PMC9688723]. However, it has been found to have potential targets associated with the cell cycle, angiogenesis, epigenetic regulation of gene expression, and chromatin remodeling [PMC9688723]. Overall, the combined expression patterns of MNX1, MNX1-AS1 (another lncRNA associated with the same locus), and MNX1-AS2 have shown diagnostic power in distinguishing normal samples from tumors across various cancer types [PMC9688723].