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Homo sapiens (human) long intergenic non-protein coding RNA 1616 (LINC01616) URS00008E3A00_9606

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LINC01616: LINC01616 is a long non-coding RNA (lncRNA) that has been found to be associated with the protein ubiquitination pathway [PMC5354861]. In a study comparing Alzheimer's disease (AD) patients with controls, LINC01616 was found to be downregulated in AD patients [PMC5354861]. Although not previously associated with AD in the LncRNADisease database, LINC01616 was identified as one of the top 20 AD-associated lncRNAs in a study by Wang et al. [PMC6182084]. In another study, LINC01616 was identified as one of the lncRNAs significantly associated with overall survival of glioblastoma multiforme (GBM) patients [PMC9098818]. Functional analysis revealed that LINC01616 promotes malignant phenotypes by enhancing cell growth, invasion, and anti-apoptosis in vitro [PMC9052012]. Additionally, it was found to be one of the downregulated lncRNAs in GBM [PMC9098818]. In a network analysis, LINC01616 was identified as one of the lncRNAs involved mainly in regulating cell cycle, mitosis, leukocyte activation during immune responses, and DNA replication [PMC9098818]. Overall, these findings suggest that LINC01616 plays a role in various disease processes and may have potential as a therapeutic target.

Genome locations

Gene Ontology annotations

Sequence

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UUUCUCAGAGGAUCUCUAUAGGCAGUUAAUAGUAGUUGAAAAAGGAACUGUUUUUGAAUUUUUGAGUUAAACAGUAAAACUAGUUUCUUUGUGGUACUUCUCAGAGCCUACAAUCUGCUAAUGUGUGUAGUGAAUUUCCAUGAGGAUGAUGUGUGGACUUUCUCACAUUUUUAAAUGUAACCCCUCCUCCUUUUAUUUUUUGGCAGAGUAUCUUAUUGGAUUUUUGUUUCAUAGAAUUUGGUCAAUGAUAUUUACAGGAUUAGAAAUAAGCAUUCUUGAAUUUUUUUUGAAAUUCUAUGAAAUAGCUCUUGGAUCUGGGCUUCUAAGAGUAUAGUUAAUGCUUCUAAAACUUUAAUAUGCCUGUACAUUUGCUGGGUAUCUUGUUAAUAUGCGGAAUUUACUUCAGUUGGUCUCCAUGGGGGCAGUGAUUUUGCAUUUCUAACGUGUUCCCAGGUGAUACUGAUGCUACUGGUGUUUUAGCAGUCUUCGAGCAGUAAGGCUCCAGAUGUAUUUAAGUGCUUUCCUAGGUGAAAAGUGUUAAAGAUAACCUCUGCCACCUGGCCUGGAGGUAAGGUGUUUAGAGAGGCUUCACCUUAGGGCACUGGAAGUUGGAGCUGAGUAAGUAGUUAUACAAGCCAGAUGAUCUACUUGUAUAUUACUAAUAAUCUGUUUAUUUUUCAUUGUAUACUUUUUCCUGGCUAUGAGAGAUACACAAACAUAUUUUCAGAAUAAAAUAGCAAAUACCUAUAUGCUUUGACACUUGCUAUGUGUCCAAAAUAUCCCAUGGCCUUUUGAGAGGUCCUUGGUAGGGGAGUUUAGAUCUCUGUUCUGUAAGCAAUAAUAUUGAAUGGGAAAUACACAUGUGGAAUGCUUAGUUAGACCUCAUUUAACCCCUUCCCUAUCUCAACAUUCAUGUCCUCAGCCGAGGACAAAGACUUAACUGACUUUCUAUGUGAAAAUGUAUCAGUGAUUCAGAAGGGGUUUUAAUUGUUUAAGGCUGGGAUAACAAUUAAGGUUUGCCUUUUGUGUUAACUCUAUACAUUUGUUCUUCAAUAUCUAAAGGGAUGUCUAUAGAAAGAUUCAAGGCUAUGGUCUGAGCUUGACGAGAGUGACACAUUAGAUUAAUGAUCUCUCUCCUGGGCAUGGGAAGGAAAAUAUCCUCACAGGAGCUGAGCUGCAUAUUUGACACCCCUGAUAAAGCAUUAGGUUAUGCUGACACCACAUUGUCUACAGAUGAUCUUUGCACCUUCUGAUUUGCUUAGUAUCCAUUGUCAAACACUUAAAUAUGGGUUAAGGCUACUAUAAAAAUUAUUUACUUAAUUAUUUACUUAUGCCAUUUUUUUUCAGUACUAAAACUGCAUUUUAGGUUGUGUGCUCAGAGUAAUUGGGCCAAGAUUCCAGUGAAAUACCUGAAUGGUGCUAAAAAUAAAUUCAAUGAAAUUCCUUUAAGUCCUUUCUCAGUGGUUAGAUUGUUUACUCCUCAAAUUCCUUGCUAACAAAUUCUUCCUAAUAGAGGUCCUGUUAGAGUCAAUUAGUUAAGAUUUAUUUAUAAUUAGAAACUCCUAUUUGCACGCAAUUGACUCUUUCAAAGUCUUUCAGUAGGUUAAGUUUGUUUUCUGCAGUUUUGAUUACAAAUACUUCAUUUUUGUUACAAAGUUAAGCUUUAGUUUAAUUCUUGGUCAUAUCAAACAUUUUAAAUUCAUUGAGUCUAAAUCAUGAGUUGAUUAUAUUAGAUUUGUGUAAUAAAGCAUUAACAAUCAUGACAGUUAAGAUGAUUCUUUUAUGUGUUAGUUCAUUGGGGCAGAAGACAGCAUAAUACAGAUGCCCAGUGUAAAGAAGUUAGCAGAUUCAAAUUAUCCAGUGGUUCACUCAACUAGAAACUCUAAUUUUUAAAGAAUGAUGUAAAAUUUGCUGGGCACUUGUGUGUACUCGCGUGCAUAUGUUCUUGUGUUGUUGGUGUAUAUUGUUCUGCUUUGUUUUGUUGUUCUUCAUAUACAUUCAAAUAAGAGCUUUUCUGACUUGGUAGUAGUAGGUCAGGAUAAAGAGCUGGGGUGUGCUAUCCCCUACUUGUGAGUUGUAUAUAAUUUGUUAGGAUUCUUUUGUGUCCACCUUUUUUUAAGUUUAGAUGGCUGGCUCUGACUGCUAUAACAAGGUAUGUAUCACAGCUAUGUAAUGUAAGAAUGCAAAAUCUACUAUAGUUGUACUAUAAAUUCAGCACCUGUUACUGUAUAAUUAAGAUACUGCAUUUGAAGACAAUAAAAAAGCUAAUUCAAAAAAAA

Taxonomic tree

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Publications