v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) long intergenic non-protein coding RNA 1588 (LINC01588) URS00007E449F_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LINC01588: LINC01588 is a long non-coding RNA (lncRNA) that has been implicated in esophageal squamous cell carcinoma (ESCC) [PMC9134121]. In ESCC patients, the expression of LINC01588 is increased compared to adjacent normal esophageal tissues [PMC9134121]. However, the involvement and function of LINC01588 in other diseases or malignancies has not been reported [PMC9134121]. Interestingly, LINC01588 is highly expressed in tumor samples compared to normal samples [PMC9134121]. In addition to ESCC, LINC01588 has also been associated with tumor grade, TNM stage, and lymphatic metastasis in patients with ESCC [PMC6859451]. The functions of LINC01588 are still unknown [PMC7350633]. Furthermore, LINC01588 expression has been negatively correlated with the PPAR signaling pathway and may act as a negative regulator of Treg cell maturation [PMC9027862]. FISH assay results showed that LINC01588 had higher expression in pemphigus lesions compared to normal tissues [PMC9027862]. Overall, LINC01588 is a lncRNA that is upregulated in ESCC and may have implications for tumor progression and immune regulation. However, further research is needed to fully understand its functions and potential therapeutic applications.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
AAAAAAUCAAGAACAGAAGUCUCUCAACAUUUAAGUUUUACAAACAAAUAGAAUCUGAGCCACUGGGUUAAACAUGACAAACGACACACAGUAACAAAUAUUGAAGACAUCAUAAUGCCAAAGCAACAGAAGCAGCACCAGAAAUGUUGCUGAGGCCACCAUUUAAUUAACGCAAGUUGAACAUAUGGCUUUGGUUACAUGUGGUUCCAGGCCAGAGGCAUGGAAGUCAGUGUUUGUGGGAAAGCCAGGAGGAAAAGCUCCUCUCCCCACCUCCACCUUGUCACUCCAGGUUCUGGUGACCCCAUCUCGGGACACGGCCUCCCAUUUCACUCCUGCACCAACCCCACUCUUGUAACACUGCACAUGCAAGAUGUGAGCAUCUUCAAAGUACGAAUAUUGCCUUCUUCAUUUUAGAAUCCAUGAUGUGCUUGUGGGGAGAAUGAAUGAAUGCUCAAACAUGAAUGGAGAGAGACAGAGAGGAAGUGCAGGUCUAACCAAGGAAACCUUCUUUCCUAGAAAAUCGUUGAUGAGCCCGGAAAGAGUUGGCUGAACAACGGUAACAAUUCUUUUAUUAUUAUUUAACUUAUUAAGUUAUUAGAAAAAGUAAAAGAGUGAGUCGAGGUUUUUGGAUUGGAAGUAGGGACCCACUGAGUUCCCUCCAGGAUUGUGGAGUUUCUUUUACAGCCACAUGUGGAUAAGAAACUAAGGGCCACAGACCAAAUGACAGGUCGGAUGGCAACCCUGGAAAAGUCACACAGCUCAGCCUGUUGGAGGAAGAGGAGCAGUAGAACCUGUGUGGAGCCUGACAGAACCCAAGAUGCCAUUCACGAACCGAGAGGUCUUUCAAGAUCACACACAGUUCUACGACACAGACAUUUCGUCUUCUUGCCACUCAGUAGCGGGGCCCAUCCCUCUGUGCCUCCAAGGUCCGUGUGCCAUGUGGAAAACUCAGGUGUUCUGUCUCUGCCAGGACCUUCUUCCUGCUGCUUAUUUAAGUGUCUGCUGCUUCGGGGCCUCAGGUGCCUGCUUUAUCUCUUUCUCCUUUACUAUCAAGUCUUUAAGCAAUUUGCCAAGACGGAGAAUCUCACUGGCCUGGUGGGGCUGAGCCUUCCUUCACUGGCUGACCAACUGGGAAGUGGGCUGCUGCCUAGAUCAGGUGCGUGCCACAGUUCAUCUAGCCGUGCCCAGAGUUCUAAGGUUAUGCGCAUGACCCCGUGUGUGGGCAGAGGCUCUUAGCAGGGGCCGAGAGCAUUGGAGGCAUCUUGAGGGCCAGAGUCCCCAGCCCCAGAUCACAGAUACGGCAUGAUCAAAAUGUGAGGGAGCAGGGGCAGAGAUUAUUUGGAAUAACGUGCUGAGUUUGUAUACUUUUGACAAUUAAAAGCCCUAUGUCCCCCUGAUGUUACGCAUAUGCUCCAGAGGAGCCACUCGGGACAAAGAAUCAAUAAUGGGCGCUUGGUGUGCAUUGAAAGCUGACAGUGUAUAUUUGUGGGGACUAUACAGGGAAAGGAAUAUGAAGCCUUGACAAGAUAUGGUGAGUAUGUAUCGGUGAGGUAGGUAACUCAUUCAUAAGGGACUUUGCAAGGUGGCAACACUGGUUCAAAGAUAUUACGAGAAUAAAGAUUUUGUGUACUCAGAGAACGAAAAGGAAUGCUGACGUAAGAUCACAAAGUUAGAUACUAAACUGGCUAAUGUGCUACAGGGCAGCAAAACUAUAACCUUUGAGGUAAUUUAUCUGACCAGAUAGGAAUCAUUUGCAUCUCUGUAGAACAGAAAAACACUUACUUUUUUUUUUUUUUUUUUUUUUUUGAGACAGUAUCUGGCUCUGUCCCCCAGGCUGGCGUGCAGUAGCAUGAUCUUGGUUUACUGCAACCUCCACCUCCUAGGCUCAAGCCAUCCUCCCACCUCAGCCUCCAGAGUAGCUGGGACUACAGGCACACACCACCAUGCCCAGCUAAUUUUUGUAUUUUUUGUAGAGAAGGGGUUUUGCCGCCAUGUUGCACAGGCUGGUCUCAAACUCUUGAGCUCAAGCCCACCUCAGCCUCUCAAAGUGCUGGGAUUAUAGGCGUGAGCUCCCGUACCCAGACAGCACUUACAUUUUAAUAGUUUCUACACAGUACUAUCUCAUGUUAUUUUAUUUUUUAAAAUCGAUAAUGGGACUCUUGCUAUGUUGCUCACACUAGUCUUGAACUCCUGGCCUCAAGCAAUCCUUCCAUCUUGGCCUCCAAAGUACUAGGGUUACAGGCAUGAGCCGGGGCUCCUGGCCUAACUAAUUUCAGAGUUAAGAACGUUUGGACUCUAUUUUAUAGUAAAAAAUAAGUCAAAGCUACCUUCCCCUAGAUAGCCAAAUGACUCUCAGAUGGGCUCGUUAGACAGUGCUUUAAUUUAAUAUUGAAAGAACUUUUUGCUUCCCCUCCUCCAAGUUUUAAUAAUUCUUAACAGAGGGAAACAGCAACAAAAUUUUUGCUGUAGUGGGUAUUAAAGAAGGGAAAACAAUCAUGAAUGCCGGAGUCAAAAUGCCCAAGGAGCGGAGGCACCAGCGUUCUCCACCUGGUUUGGCGGCGCACCAGCAGUGUGACCUGGAAUCUGAUCUCUCUGGAGCUCAGUGUCCUCACCUAUAAUAUGGGGUAUUGAACUACACACUUGGCAGGACUUUGCCCUAAAGCUAAUUUUCAAAAUAAAAAAAAAAAAGCCACUUCCCUUUUCCCACAUUAACCCUGAGAGAGAAAGAGGAAGCGGGAAGCCCGCACAUGGAAGCAAUUUAUUGCAGACGUUCCUGGGCUGGGAGAGGAGCCUUCUGACUGCUGCAGAGACCAUCACCCGGUCCUGCACCUUUACCGGAGGUGCGGAGAACUGCUCGGCCCGCACCGGGCUCGGGGGUGUUCACGGGCUGCGCUGCCUCCCCUGCGCGCAGGACAGGAGUCGCCAGAGGCCGGUGGUGGAUUUCCUCCCCGCAUCUCAGCUCUCCGUCCAAAGUCAAAUUGCUCUUUUCUCCGCCCACGCGGGCGUGGCAGCUGAUAUCCGGCCGCUGGGCGUCCCCGCGCCCCCGGGGGCCCCGCCCUGCAGCUAUCUCCGCGGCCCACCCGGCGGCGCCUCCCUGCAGGGCUGCUCCCCAGCCCAAACCGCCGCGGCGCGACGUGGAGCCAGCCCCGCAAAGCUGCAUCCACCCCCCGAGGACCAGCCCCUCGAAGGCAAGGCCAGGACCUCCCCGGGCGGCUGCAGCCGUGAGCCACCCCUGUUUUGUGAAACACACACUCUGCCAUUUCAGGCCGCACUUGCCCGUUGCCAUGGGCGUUUUCUAUGUUGACACAAGCAGGGACACGGAAUCCCUUGACUUUGAGUUGCAGAUCGUGGGUGUUGGCGUCUCCGCUGCUUUACCAGGAAGGAUGGAAGGGGCUUCAGCCUCCAUUCUCACUUUCCUUCUCAAGGAGUUGGCUAAGCAUCAGGAGUUUUCUCUUAGGCUUCUCUCAGGUCCCCUUUCCCUGAGAGGUGAAAAGUUUUUCAGAAAGGUGAGCAGCUUUCUCUUUAUUCCCAGGGACCACUUCACACACCCCUUUUUCGCCUCCAGAGUAGAUGGAACCGUGGAACGAGGGAAUCCUGCCCUCUGGUUGUGUCUGUCAUCUCCUACUGGGACCAGAGCCACAAAAGCCACAAAAGACCCAACUCUCUCCAGCGUGCAGGCAUCCCAACUAGAGGAAGCAAGGAGGCAGAGACCAAGAGGACAUCAAGAGGCGUUUGAACCCGCAGAGAGGGCCUGGGAGCACAAUGCUGAGCCCCUUUGAUUUCAGGAAGCUGUGGACCGUGUUUAGCCUGUGGCUCUGUGUGCCCCUUGGCUGCUGCUGCUGCUUACUCCUGAGGGUGAAGUUGCUAACAUAAGAAACGAGUAAUUUGGAUUUGCGCUUCUUGGAGAAAGAAUUGUGCCAUGAAAAAUGGAAAACUCCUGAGAAGCUGUUCCAGCGUCAGGAGAGCAGCAGACAAGCUGGACUGGGGAAGAUUCUUCCUGCAAGACCUGCAGAGUGUAUGACACAUAACCAGCACCCAAGAAAUGUCUACCGAGGAAUUAAUGAAUGAGCCAUCUUGUGAUCAUCUGGCAAGACAGCCCAAGAAUAAAGCCGUCACCAUGGAGACUAAGAAGAGACAGAAAGACACUGGGUCUUCAUUGUCUCGUCCAGCUGUUCAUGAGGCCUUAUCUGAAGCCCACGUGACCUCCGGACUACUCACUUACAUGAGAGAAUAAAGCUCUUUUUUGUUUAGACCAAAUAAAUACAUAAUACAAUUACAUAAUCCCUUGAUUCCUUUUUAUGACUGAGCUCAGAGACUAUAUUUUGUCAUUUUAAAUCACCUUUGUCUUACAGUUUAUUUAACUGAAACAAAUAAACAAACCAAAACACGCCAGUUUUUCACUCCUCUGUCAAAGCCUUUCCAAGAUCACUAAGCUUGUGAUGUCCUGGGUGAAUGAAGAAGUAACAGUGUUUUCAACAACAUAGAAGCUUAUUUCUCUCUCAUAUAAAAGAAGGCUGGAGUCUGGCUGGUAUGGGAGAUACAGCAUCAUCAAAGUUUUAUCUUUUCGUCCUGCCAUCCUUAGAAUAUGGCUUUCAUCUUCAAGAUCACUUCCUAAGCUAUGAGGAUGCAAAGGUAUAAGAAUGACAUAGCGGACUUUGGGGACUCGGUGUGGGGAGAAGUUGGGAGGGGUGAGGGAUAAGAGACUACAUAUUGGGUACAGUGUACACUGCUCUAAAAUCUCAGAAAUCACCACCAAAGAACCUAUCCGUGGAAUCAAAAACCACCUAUACCCCCAAAACCACUGAAAUAAAACUAAAAAUUAAUUAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications