v24

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Homo sapiens (human) family with sequence similarity 106 member A (FAM106A) URS000075F0DD_9606

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FAM106A: FAM106A is a gene that has been identified as one of the 13 genes used to construct a prognostic model [PMC9152364]. Little is known about the function of FAM106A in biological processes, and further experimental work is required [PMC9152364]. FAM106A has been found to be targeted by miR-185-5p in SARS-CoV-2 infection [PMC7664154]. In T-cells, FAM106A has higher expression with worse sleep-disordered breathing (SDB) phenotypes, while weak associations are observed in PBMCs and monocytes [PMC9889381]. In subgroup C, deletion of the FAM106A region was observed [PMC8857546]. FAM106A is one of the 10 CNV-lncRNAs significantly associated with coding genes in osteosarcoma [PMC8976607]. It has been found to interact with miRNA let-7c, let-7f, and miRNA-185-5p, which are involved in various signaling pathways [PMC8518135]. SARS-CoV-2 infection may induce the downregulation of FAM106A via direct nucleotide binding, leading to overexpression of FAM106A-target miRNAs and pro-inflammatory and pro-fibrotic events [PMC8518135]. References: [PMC9152364] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152364/ [PMC7664154] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664154/ [PMC9889381] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889381/ [PMC8857546] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857546/ [PM8976607] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976607/ [PMC8518135] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518135/

Genome locations

Gene Ontology annotations

Sequence

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ACAACUGGCCUGACCUUCAAAGGCCUUCACAGCUCCUGCCUUCAUGUUACCGUCUACUAUGUUCCUCGUGCACCUUCCACUCAGCACAAACAGGCUGCACUGCCUCCGAAACACAUCACUUGAAUCCUACCUCUGCUCCUUUGUCCAUCUGAAUCACCCUCUCCACAUUUCUGACCGUGUAAUCCUGAUCUCACUUCAUGAGGCAGUUCGCUUCUCUUUUGCAUUUAGCUUUCCCCGGGGUACACUGUCAAUAGCCUACUGUCUGAUGUCAUCAGUCAGCACUUCAUCAGAGGCAAUUAUGUCCACAGAGCUUUUGGCUAAUUACUGUCACUCCUCUUUACAUGUGUGCAUAUGCAUAUCAUCUUUCCCUAAUGAGACUGGAAAUCAUGAUUCAUUCCCUGGAGCAGUGGUUUCCAUAAGUGACCAACCCACAGACCAGUGCAAACUGGCUGCAAAAGAGCUUCCUCUGAGGAACUUAUUAGAAUGCAGAUUCUUUGACUGCAUGGGAGAGGAGGAUCUCAUAAAUCUGGGUGUAAUAGGCACAGAACGUUAGGUGUAAUAUGGGCGGGACUCUGGACUCAGCAUAUCCAACAAGCUGCUGGCUGAUUCCGACGAUGCCGAUGAAUUGCCAGGUUGGGAACUGCUGCCCCCAGAGAACCUAGCAGAGAGCUCUGUACGUGGUAGGUGCUCACUCCCCUAUUGUUUGGGUGUAUGCCUCCUGAUAAUGAACUUGAUCGUAACUUUAUUGUUGUAUUAUGCCUGUAUUGUUUCCUUAAGUGAAGGAAGAAUGCUUUUGAGUACCUAAUAGGUGGCAAGCUCUGUGCCUACUUACAUACAUGAACUAUUCCUUUUAAUAACCUUUGGAAAUAAAGUGGCAUUUCCAUUGGGCAUUAGAAAUCUGAAGACUUUCGUUUACAGCUGUUGCAACAGCAGAACUAGAAUUCGACCUCCGACAUUUCUGCUCACCAGAGGGCAUGAACUGCUGGUUUGUACCUGGCUUGCAGAUACCUUCUUUGGGCAGCACAAUGUUCAAAAUUAAAAAAACUACCAACACUUCUAAACUGGAUACUUUGUAUCAAUAUCUGGGUUUCUGGCUUCUCUUCACGGGAAAAAAACAAACAAACAAAAAGGUUUGGUGAACACUGGGGCCCACAUUCCUGCAGGGCAACAGUCACAUGGAGACUUUAGAUGGGCACGUGCCCAGAACACACUAGAGUCCCCAUCGCUCCCCAUUCUCUUACAUUCUGUUCCCAACUAGGUUCUUAUAGGCCUGGGUUUGUGCCUGUUGCACACUUAUCUACUCUCUUGCUUCCCACUGGUCAGGAAGUCUGGCAAACUUAAAAGGCCUCUUUUUGUUGCUCUCUUCUGUAUGGAUCUCUCAUCAUAGAGGUGUGUGCAUUUCUGACUUUGUGAUUUCAAUACUAAGGAAGCUGUCGGCAGAUUAUCAAGGAAAACGGGGAUCGCUGCUCCCCAACGUACACAUUCUGGUGUGCCCCAGUAAAAUUCUAUAUUCAGCCUCCAAACUAGCUGGGAAAAAUGUGGCAAAUCAUCUACUUGCUCCAAUUCAAUGGUGUUUAGAAGUAGGAAGUCACUGUGAGCAAUGCCACCAAGUGGUGGAGAGACUCCAUGCAGAAUCGCCACCUUCAGCCAGAGAGGCUGGGAGGCCGAAGACCUCUCUCAAUGCACAGGGCCAUUCAGAAACUAGAAACAAAAUGCUUGCUCAUCUCCCUAGGCCACUCCUUCCGAGGCUUUUUGAGACGAGGUCUCACUGUCACCCAGGCCGGAGUGCAGUGGCACAAUCAAGGCUCACUGCAACCUCAACCUUCUGGGUUCAAGCGAUCCUCCCACUUCAGCCUUUCAAGUAGCUGGGAUGACUACAGGCAUGGGCCACCACAGCCAGCUGAUUUUUUUUUUCUUUUUAGUAGAAAUGAGGUCUCGCCAUAUUGCUCAGACUGGUCUUGAACCAACACAUCUUUAGCUUUUUAAAAGACAGCCUUGGCCAGCCAUGGCAGCUCACACUUGUAAUCACUGCACUUUCGGAAGCUGAGGUGGGCAGAUAGCUUGAGCCGAGGAGUUCAAGACCAGCCUGGGCAACAUGGUGAAACCCCAUCUCUACAAAAAAUACAAAAAUUAGCUGGGUGUGAUGGUGCACAUCUGUGGUCCCAGCUACUGGGGAGGCUGAGGUGGGAGGAUUGCUUGAGCCUGGGAGGUCGAGGCUGCAGUGAGCUGUGAUUACCUCACUGCAUUCCAGCCUGGGCAACAGAGAACCCUGUCUCUAUUU

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Publications