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Homo sapiens (human) family with sequence similarity 74 member A3 (FAM74A3) URS000075DBA9_9606

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FAM74A3: FAM74A3 is a long non-coding RNA (lncRNA) gene that has not been fully characterized [PMC9306206]. In a Cox-based search, a lncRNA signature consisting of LINC00705, LINC00310, LINC00704, LINC00574, FAM74A3, UMODL1-AS1, ARRDC1-AS1, HAR1A and LINC00323 was generated [PMC4991477]. In breast cancer patients, the upregulation of nine lncRNAs including FAM74A3 was found to be associated with tumor recurrence [PMC5668502]. In PFA tumors, FAM74A3 was identified as one of the hypoDMR upregulated genes [PMC9637194]. The upregulation of the lncRNA signature that includes FAM74A3 has been shown to predict recurrence in breast cancer patients [PMC6111859]. Additionally, FAM185BP and TMEM121 were found to be extremely significant selection signals in M.Yunnan.West populations along with FAM74A3 [PMC9306206]. References: - [PMC4991477]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991477/ - [PMC5668502]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668502/ - [PMC9637194]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637194/ - [PMC6111859]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111859/ - [PM9306206]: https://www.ncbi.nlm.nih.gov/pmc/articles/PM9306206/

Genome locations

Gene Ontology annotations

Sequence

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GCUGCCAUUGCGGAUUUUGCCAGCUUCAGCCAGUUUAGUCCUAAGAAGGAACUUCUGACCCCAGACAUCCUGUUUUCUAAAACUAAGCAGUUAAAGCUGAAUGGGAAUUUAGCUCUGUCACAUAGGCAUUGGUUGGGCAACAAAAGCAGGGUAGGGCUCCAGCUAAGCCACGUAGGCACUACGAUGGGCAACAGAAAGGUUGGUUUCUGGGCAAUUCAGAGAAACCAAGGACAGCUACCCCCAGAACUCAGAGUAGCCAACUGGGCUGCUCACAGGAGAUGCCUUAACUGAAAGGUGAUCAGACUCCACAGGAGACCCAGAGAAGAUGUGGAGGGAGCUCAGAGGUUGUCCUGGAGGAGACGUGGAGACAGCUCAGAGGCUGUCCCGGAGAAGACGUGGAAAGAGCUCAGAGGCUGUCCCAGAGAAGACGUGGAGAGCUCAGAGGAUGUCCCAAACAAGAGAGAGCUCAGAGGCUGUCCCAGAGAAGACGUGGAGAGAGUUCAGAGGCUGUCCCGGAGAAGACGUGGAAAGAGCUCAGAAACUCAGAGACUGUCCCGGAGAAGACAUGGAAACAGCUCAGACGCUGUCUGCAAGAAGACGUGCAGAGAGUUCAGAGGCUGUCCCGGAGAAGACAUGGAGAGAGCUCAAAGGCUGUCCACAAGAAGAUGUGGAGAGAGUUCAGAGGCUGUCGUUACUGCUGCACUUGGCUGUUUUUCUUUGGAUAAUUAUUGCCAUCAAUUUUAGUAAUUCAGGUGUUAAAUCACAGUCAAGCACCUAUUUACCUAGUGGUAAAAUCCUUAAGUAAGUCAUAUUUGGUUGGGAAGAUCAAAGAAAUCACCCAGUCUCCCACAUCCGAAAUUGUGCAGUCUGGACUGUCAGGAACAAAAGUGAAAGAGAGACGUCAUCAAGGCCGGGCGCGGUGGCUCAUGCCUGUAAUCCCAGCACUUUGGAAGGCCAAGGAGGGCGGAUCAUGAGGUCAGGAGUUCAAGACCAGCCUGGCCAAUAUGGUGAAACCCUGUCUCUACUAAAAAUACAAAAAUUAGCCAGGCGUGGUGGCAGGCGCCUGUAAUCCCAGCUACUUGGGAGGCUGAGGCAGAAGAAUCACUUGAACCUGAGAGGCAGAGGUUGCAAUAAGCCAAGAUUGUGCCAUUGCACUCCAGCCUGGGAGACAAAGCGAGACUCCAUCUCAAAAAAAAAAAAAAAAAAAGAAUGACUAAAAUUAAGAAGAUUGAUGAUUCCAAAUAUUAGUAAAGAUGUAGAACAACUAGAACUCCCACAUAUUGCUGAUGAAAAUGAAGAAUAAUACAUUACUUUGGAAAAUACUUUGGUACUGAUUUACCAUAUGACCCCAAAAUCUCACUUGUAGAAAUUUAUACAGGAAAAAUGAAAACAUAUGCUCACAGAAAGCUUGUAUACACAUGCUUAUGGCAAUAAAUUUAUUUAUAGUUGCCUACCAACAAGUGAUGAACAAAUAUAUUUUAGUAUCUUGAUACUACUUUCUAGCUAGAAAAGGAAUACUACUAAGCAAAAAUAGAGGAUGAAGUAGUAAUAUACAUAACAUAGAUGAAUUUAAAAACACCAUGCUGAUUGAAAGAAAACAAUUAUCAAAUACACAGUGUAAUAUUCUAUUCACAGAAAGUUUGAAAACAAAAAACUAUAGUCUCUGAAAGAAAACCAUUGGUUGCAGGAAGGUGGGGAUUCAUUGGCCACAAAAGGGACUGAGGAAACUUUUUAUGGGUAAUGGAAAUAUUUUAUAUCUUGAUUGUGGCACCAAUUAUACAACUGUAUGUACACAUCUGUCAAAAUUCUAAUUGUAUUAUACACAACAUGAGUGACUUUAACUGUCUAUAAAUUAUAUCUCAAUAAAAUUGGUCUUAAAAGAU

Taxonomic tree

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Publications