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hsa-mir-587: Hsa-mir-587 is a microRNA that has been identified as a potential regulator of multiple genes. It has been predicted to target six out of seven genes, including EPS15, and five out of seven genes, including TGFβR2 and SMAD4 [PMC4838358] [PMC6874787]. Hsa-mir-587 has also been found to be shared between TLR4 and NRP1, and is associated with ACE2 networks in the diagnosis of COVID-19 [PMC8722767]. It is one of the top miRNAs regulating ACE2 networks, along with hsa-miR-302c-5p, hsa-miR-27a-3p, hsa-miR-1305, hsa-miR-26b-5p [PMC9742611] [PMC7480227]. Hsa-mir-587 is not directly involved in GBM but is associated with major cancer types and diseases [PMC5260001]. It has also been identified by multiple algorithms as a regulator of ACE2 networks [PMC7367724]. Additionally, hsa-mir-587 has been predicted to target ACE2 along with other miRNAs such as hsa-miR-588 and hsa-miR5825p [PMC7700842]. In the context of T1D, it targets DKK1 along with other miRNAs such as hsa-mir941 and hsa-mir5613p. HSA-MIR587 was also found to be one of the candidate genes within the linked region for hearing loss [PMC4510537]
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Gene Ontology annotations
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