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MIR1973: MIR1973 is a microRNA that is involved in various biological processes. It has been found to be associated with the translocation associated membrane protein 1-like 1 (TRAM1L1) gene [PMC4852408]. The expression pattern of MIR1973 in alveolar type II (ATII) cells from emphysema patients and controls was similar to that of 16S rRNA, suggesting a direct link between MIR1973 and long non-coding RNAs (lncRNAs) [PMC9313339]. The levels of MIR1973 and miR4485-3p, which are partially derived from MT-RNR2 gene transcripts, were analyzed [PMC9313339]. Increased levels of MIR1973 were found in patients with chronic obstructive pulmonary disease (COPD) compared to smokers [PMC9313339]. In emphysema, the expression of MIR1973 was decreased in ATII cells compared to smokers and was lower in nonsmokers than in smokers [PMC9313339]. In a dataset analysis, MIR1973 was not represented [PMC7425458]. CpGs within 10,000 bp of a gene were identified, including two CpGs mapped to NLRC5 and MIR1973 within 1,500 bp of transcription start sites [PMC7425458]. Furthermore, the expression of MIR1973 has been shown to increase resistance in lung adenocarcinoma cells with subsequent low apoptosis intensity [PMC7425458].
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