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Homo sapiens (human) SATB2 antisense RNA 1 (SATB2-AS1) URS000075CE4D_9606

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SATB2-AS1: SATB2-AS1 is a long non-coding RNA (lncRNA) that has been studied through bioinformatics analysis [PMC10148439]. This analysis revealed a conserved binding site of miR-3678-3p on SATB2-AS1 [PMC10148439]. In terms of its mechanism, SATB2-AS1 has been found to promote SATB2 expression by acting as a molecular scaffold of WDR5 and GADD45A in the cell nucleus and recruiting them to the promoter of SATB2 [PMC6729021]. SATB2-AS1 is an lncRNA that plays a role in gene regulation and has been found to have conserved binding sites for miR-3678-3p [PMC10148439]. This suggests that miR-3678-3p may interact with SATB2-AS1, potentially affecting its function or expression. Additionally, SATB2-AS1 has been shown to act as a molecular scaffold for WDR5 and GADD45A, two proteins involved in gene regulation [PMC6729021]. By recruiting these proteins to the promoter of SATB2, SATB2-AS1 can promote the expression of the SATB2 gene. These findings provide insights into the role of SATB2-AS1 in gene regulation and highlight its potential as a therapeutic target. Further research is needed to fully understand the mechanisms by which SATB2-AS1 functions and how it may be involved in disease processes.

Genome locations

Gene Ontology annotations

Sequence

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ACUUGAAACAUUCUGAGUGUGCCUGCAGUAGGGUCUCAGAGGAGUUGCUCUGAAAGCUGUUGAGAGCAGCCACCUUUGCUGUCACUGAGAGCUUGGCAGGGUCAGCUCUGGUGGGCCGUUUGCACCCAGGCUCUGAUGGCACCAGGAUGGCUUCCUGCAACCCGGAACCUGAUCCUGGCCCCCGGCAGAGCAUAAGGGCCCGAGGCCAGGGACCUAGAGGCCGGACCAAGUUCGCGCGAGGUGUUCACAGCCUAGGCGCCCCGGGCUUGGCUUCGUACUCUGCAACAAGCCAAGCUCCCUUGCCACGAGUAUAUCAGCAACUUCAGAAAUAAACACCAGCGAAACCCCUUCCCACAUUAGCUUGUUGCUGUGCUACUGACACUGGGCUUAGUCGAUGUUCACACCUAUUACAUUUUUCCGGAAAGUGGGAGGAGCAGGGGGUAGAGAAAGCUGUGUGUAUUGAGGGAAGGGGAGAUGUGUGCAACACCUUCCAGAAAAAUGGGGAGGUAGUUUAGAAAGUUUUUCUCUGUAACAGCACAGCUUCUGAGAAGGCAGAGAGAAGAAAGCAGACAGGAAACGAAUCCCUUCCUCCUCUCCCCUUUACCCCCUUCCUUCACUCCCUAGACCAAGCUGGUCACCCGGCUGGGAAUCAAGAUUGUGUGGCUGGGAAGACACCAGUCUCUGUGCUCGGGUUCAGCCCAGUCGGGCAAGAAAGUCUGGGCAGCUGGAGAAGGUCGUCACAGUCUCCCGUGGAAUCUUGUUGCCUGAGAGCCCCAUAACGGAAAGGGCUAAGACGACUCUUCCACACACAGGUCGCAGCCCCUGCCGCGGAGGAUCCCCAGGAAGAUGCUGGGGACGCUCUGAGCAUCGGCCUUUCUUUACCCCCGACUCCCUGGAGCUUGGUCUCGGGAUGCCAACUUGGGGCACGGAGGCGACGGGCUGCUCCGAAGCUGGAGGGUUUCUGCUUGGGUCAGAGGGAUCACGACCUCAGCAGAGCCAGGAGAGGUUGGGUGACACCCACUGCGUAUUGCACUUGACUCAAAACUGCCCUCGGCCUGCGGAAGAGGCGAGGGCAAGAAGCCUGGUGGCGGGUCAAACCUUCACCCUAUUAUUUUCUAUCAUUUUUUAUGCCCAUAUAUUUGUUAAAUGUAUGGCUGCUAUACACCAACAGCUUAUUCUACAAGAAGUGCCCCCGAGGAGGAUUGGGUUAAGCUUUGCAAAUUUGGCUUCCCAGGUAAUGCGCUUCAUUAUUCUGCUCCCGACUUACCCACCACACCAGUGGGUACCCGGAGCAGCACCCACUUGGCAGAACUGAUGACUGCUUGGGCCCAGCGGAGUGCGCAUUGCGCUAACACGCGCACGGGAAUUGCACCCUUGCCGGAGCCUCCGCACCGUGCGCCCUUCAAAGAGCUGGCGACCCCGCUCACGUGUAAGCAACCUCCCACUUUGAAACUAAUUCGCACCCGGGUCUUUCACCCCAAAGGACUUUGCUGCGGACGCUGCUCUGACCCAAGACGCGGGAGAGAAGUCCCAAAGGCUACAGCCAGGGGCUGGGGGACUCCUCUGCUCACCUUAGUCCUUGAUUUCGAAGGCCCCAAUUAACUAUCUGUUGUGUCAGAAUCGGCGAGUGCAAAGUAGCUGCGCCCCGCUGACGCGCUCUCUCCUGGGUCCGGGUAUCCCAGGGCAUCCGGAGCUGGGGAGGGUUGUGCGGACUACCCAAGGCACGCGCAGAUACCGGGCAGGGAAGAAGGGCUCCGUGUUCCAAGGAUGGUCGUUUACCUCUCCUGAGAUCAGCCCUAAUCCCUUGGUAACUUAAGCGCCUCUGAACUCGGGGAGCGCUUGGUGGGGCGCCUCCCUGCAUCCACCCCUACCCCUGGCUCCUUCCCAGGCCCAGCAUCUUUCCCACCAUUCUCACCCCCACCACCCCCACGGCCCCGCCCGUUUAGAGGCGUGCGGUGGGCACUUGGUUUACAGAACCGGCGUUUCAGAUGUUUAUUUGCAACUAAUUUCUUGUGCUGGAAAAUGCUUGUUACCCGGGCGGAGCGCUUCCGCUCUGCGCGGUCCGGCCCGGCGGGCGGUAGCUCGCUGAUCCCUCCGGCGAAGCCUCCAAGGAGCGGGCGGCUGGGAGAGGUUGUGCCACCCGGGACCAAGCCAUCGGCGCUGCUCCGGACUCCCGGUAGGGGGAGCCGCCGCGGGCGCCAGGCCGGAUUGUGUUCUGGCCUCGGGGCGGCCCUGCUGCCAGCGGCCGGGACUCUCAGCACAGAGCUCGGGAGGACUCCACCUGCUCUCCAGAUAAGGCGCCAUGAGCAGAGAAGGGAACAGACGGCCAAGCUCCCUCCUAAUUCCCCGUUGUUGCAGAGCAAAGAAGAUGGGGGAGAACUAAUUAUAUUCUCUAGGUCUAAAUAUUGUUGAAAAAUUUGUAGGUGAGAUCACCUCCUUUGCCCAUAUCCAUAUAUAAUAUAUCCAUUACAUGUGUUUGCCCAUAUAUAUACGUAUGCCAUAUGUAAAUAUGUACGAGUGUGUAUGUAUGUGUAUAGCAGUGGUUUAGAAUUAGUCUCAGUUCCACAAAUUUUGAGCCCUUUUAAUAUUUUAGGUGACCUAAUACCUUCUCACUGUAUUUUCCAAGUCACUUAUUUCCAAGAGUUUUAGGUGAUCCCAGCAUAGGAGCUGAGCAUAGGAGCUCAGAUGAGACUUGCCAGUUUUGCUGCAGUAAUGUCAGCAAAAGAGUCUCUCUCUUUCUGACUCUAUAGACUUAAGUAAGGGUUUACAGGCUUUCAUUUUAAGGUAUGACUGAUAUUUAGAGAACAAGACUAAACCAAGGUCAAGGGGAAAACAGUUAGACUGUGAACCUGCAGACCACUCCACUGCACCCAGUGUGGCCGUACACCUGUGCUGAACGGCCAGAGACUUCCUGGUCAAUACUCCCACAGAUAAAAGACUGCAGGAUCUGCUUAUACACAAAUCCAUCUUUCGCUGGGAACCCACAACUCAUAACAACUCUCCUAAUGCCAAGUCAUCAAGGCCUCUUGAAAGAGAAUCAUAAAAAACAAAGAAUUUCAAACUUGGAAGGAAACCUAAAGUUUACUGGUGAGGAGCUUGAACUGAGUAGAAGCAAAGAAUCAUACUCCAGAUGAGAAACGCCCCAUGCACUGAGCUGAGACUGGAACUCUCCUCUUCUUACUCUCAGUCCAGUAAGUUUGACUACAGAGCACUCAUUAUCAUUGUGAUUAUUAUGUUCCCGCAUAUUUUGUCGUUCUUAGUUAGGCAUACUCCUUUAACACUAUUGUAAUAAAAGCAAAAUCUGGAAGAUCUUUAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications