rno-mir-122: Rno-mir-122 is a microRNA that was used in a study to investigate its effects on injuries induced by CCl4 in animals [PMC9513290]. The study involved injecting animals with either rno-mir-122 mimic or a negative control [PMC9513290]. The serum levels of rno-mir-122, along with rno-miR-9a-5p and rno-miR-192-5p, increased significantly 8 hours after injection and reached peak levels at 24 hours before returning to baseline levels at 72 hours [PMC4366852]. The baseline levels of rno-mir-122 were low, indicating that it may serve as a housekeeping miRNA for the liver [PMC4366852] [PMC5465221]. Despite its abundant expression in the rat livers, there was no differential expression of rno-mir-122 compared to the control animals, suggesting that it may not be relevant to the treatment effects [PMC5465221]. However, it was found to be one of the top ten most abundant miRNAs in the livers across all treatment conditions [PMC5465221]. The microRNA levels were assessed using the TaqMan MicroRNA assay with specific primers for various mature miRNAs including rno-mir-122 [PMC3864878]. References: [PMC9513290] - Study on injuries induced by CCl4 and effects of rno-mir-122 mimic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513290/ [PMC4366852] - Study on serum levels of various miRNAs including rno-miR9a5p and rnomiR1925p: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366852/ [PMC5465221] - Study on differential expression and relevance of rno-mir-122: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465221/ [PMC3864878] - Study on microRNA levels using TaqMan MicroRNA assay: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864878/