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Homo sapiens (human) ZFHX4 antisense RNA 1 (ZFHX4-AS1) URS000075CAFC_9606

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ZFHX4-AS1: ZFHX4-AS1 is a long non-coding RNA that has been studied in various types of tumors, including uterine corpus endometrial carcinoma (UCEC), stomach adenocarcinoma (STAD), sarcoma (SARC), ovarian serous cystadenocarcinoma (OV), adrenocortical carcinoma (ACC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), and bladder urothelial carcinoma (BLCA) [PMC9251081]. It has been found to be related to long-term survival in these tumors, suggesting its potential as a prognostic biomarker [PMC9251081]. In ovarian cancer patients, ZFHX4-AS1 has been shown to be an independent prognostic factor for overall survival and its expression is related to age and clinical stage [PMC9251081]. Furthermore, ZFHX4-AS1 expression is higher in advanced ovarian cancer specimens compared to early-stage specimens [PMC9251081]. In addition to its role in ovarian cancer progression, ZFHX4-AS1 may also play a role in breast cancer and tumor-immune interactions [PMC9251081]. The function of ZFHX4-AS1 in tumors is not well-studied, but it may be involved in tumor progression and the immune microenvironment [PMC9251081]. Overall, the findings suggest that ZFHX4-AS1 could serve as an independent predictor of clinical outcome and may have potential implications for the development of new-targeted drugs for immunotherapy [PMC9251081].

Genome locations

Gene Ontology annotations

Sequence

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UGUGAGUGUGUCUCUGUGUGUGUAGGGGUCGAGGUGGGGGGGGUCCGUGUUUGCGAUCUGAACCUUUGGUACCUACAAGGAGGGUGUCUCACCGAACGGUAGCUAAAACCUCACCAGAACCGCGCGGAAGUGAGAAGUCGCGGCCAAAGGCGCCCGCAGAAGCCUCCUCUCUGGGCCGGACCCCAGCCCGAGCGGCCGAAAGGAGCCCCCCGCCCGGAUCACAGCUGCUGCAGCUGCCGCUGAAAUUCGCUGUGGCCGCUGCCUCUUCCCGCUUUAAUCCCAGACCUCCAGUCAUUGGGCAGCUCCUCAGAGGCAAGAAGUCAACACCAUGGCAACCCGACAAGCCUAUCAAAUCACCGGCUGGCGUGACAGCAGCAACACUGCAGGCAGGAGUGGGCUGGGCGGAAGAGCAGAGUGGCCACUGCGCUCAGAAGUUUACAAGGAAAGGGGAAAUGUCUGAAAUGGAGAUUGCACAAUCCUGUCUUGAAGCAGAAGACUCAGCUAGAGCACAUCUGGAAACACCUGGCACUCCUCAAUAGAAUUCAAAUGCUAUUUUAAAAGAGUCCAUUUCUAAGAAGAUGUGGUUCGAACAUACAGAGCUACAUAAUAUGAGUAAAAUAGGACCUAACAGUAGUGUUCUCCAGCAUUGCUCUGCCUUUCCUUUUCUGGAUGUAACAACAUUACUAAGAAAGGAAGAAAAAGCAAAAAUCUGCUCUCGGGGAGAUUCCAGAAUGUUGGAAAGCCCCAAAUGGAAGUCUCUGCUUUGGUUACAGGACAUAAGGUUUAAUAAAUAAAAAGAUGCUCAUCUGGGAUGCUGCACCAAUUAUCAUGUACUAAAUAAGGUUACCUACUUCACUCUCCAGGUAGAAAUGUCUAUCAUAAGCAUGUGCCACAGAAGGUCUCUCAAGUAUCAUUAUUGGCUGUGUUGAAUUUUGUUUUUAGUUCUCUUUUAUAAGGUCUGUAGUCUUACUUUCAGUGAGGAAGUGUUUUCUCAGGUUCUCAAGAAAGUAACAAAAUGCCAGCAUUGUCAAGGUCACCAUUGCCACUGAAUUAUCUUACUGUCUGAUUAUUCCAUCUUCCUCUGCAUCAUAUUAGCCUGAUGACUACAUUCUAAUUAUUUAAAGCGUUAUGUAAAUCAAAGCAGUAAAUGUAAUUUCUAGUCUUACUAGAUAUCAUGUACAUUAGGUCGAAUAACUCUAGAAAUGUCGUCAUAAUCAUGUCAUGCCUAAUGAUGACCUACUCAGCCCCUGCCAACAUCAUUCAAUUACUCAUUUCAGUAUUGAUUUUUCUCAUGCCUCUCUUCGUGGCAUUUAAACAGCCCUCACAUCUCCCCUUUUACUGAGGUGUAAUGUUGUAUAAUGACAGAGAUGCUUUGCUUCCCAGAUUCAUAAUGUUACACUCUGUUUCAAAUCCUUUUGGAGACAAAUUGGGGAAUCAAUAUAUAAAUAAUGACACACUUAUUUUUAAUUAAAAUCACUGCUUUCACAGAAAUGGUAUAUUAAAAUUAUUUUUGCUAAAAAAAUUUUAAAUACCUAUGUACGAUAAAAAGACUGCCAAUCCUUGGGAUCAAGAAUAUAAUUUGCCCCAAAUAACUUUUCUGUAAAAGUAGAAUUCUUAAUGGAAAAUAGAUUAAUACAUAUAAUUUCAAGAUCUAACCUUAAAAAUGGAAAUAAUGUGUCCAUUUUUAAAAAUAAAUCAUAUUUACAUACAAAAAAAAAAAAAAA

Taxonomic tree

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Publications