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Homo sapiens (human) long intergenic non-protein coding RNA 891 (LINC00891) URS000075B2AA_9606

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LINC00891: LINC00891, a long non-coding RNA (lncRNA), has been investigated in relation to tumor growth and development [PMC9828389]. The expression of LINC00891 was found to be upregulated after transfection with pcDNA-LINC00891 and significantly reduced after transfection with LINC00891 siRNA [PMC9828389]. Silencing of LINC00891 was observed to have a prominent effect on tumor volume and weight in mice within 28 days, indicating its potential role in tumor suppression [PMC9828389]. The study utilized GAPDH as the internal reference for GATA2 and LINC00891, and U6 as the internal reference for miR-128-3p, ensuring accurate quantification of gene expression levels [PMC9828389]. These findings suggest that LINC00891 may play a crucial role in tumor growth regulation, making it a potential target for therapeutic interventions [PMC9828389]. However, further research is needed to fully understand the mechanisms by which LINC00891 influences tumor development and progression [PMC9828389].

Genome locations

Gene Ontology annotations

Sequence

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CUUGGCGUUCACUGCAAGCUAUAAGCUCUGCAAGUGGUGACCCCGACGUGAUCGCCUUGAAGUUACGCGUGAAGGAGGAGAGCUCAUUACUUUUCGGGGAAUCCUGAGAACAGGACCAGUCGUUGGAGAACCAACCAACAAUGAUGGUGAUGACUCGGAAGGCACCUGACAUCACCUGGGGACAGCUAAAGAAAUUGAAUCAACAAGCAUCUAUCCAGCUUGCCGCCGUGGAAGCCCCUGCAACUGCAGACAAUCGGUUUCUUACAUAUCUGGUGGCAAUUGGGGAAACUUCUGAGAAAGUAAGACAGACAUGGAUGUUGGGGUGGCAGGCACUUGCAGAUGGCUCUGUGCUGCCACCCGACGCAUCUAUGACCAGGGAAGAAUCAUGGAAGCUUACCUUGCAUUGGAUGACCAGCACGCUAUAAGAAUUAAAGAAGGGGGGAAUAUGGCGGGGUGCACGACAGCAUAUUCAAGCUUAUGUACAAGGCGUUUGAGGUCGGGGCAUGGAAACAUACUGAGGCACUGUGUGUAUGUUAUUUGUGCAUGAGAAUGAAACUCCUUGACCCUGAAAACAGGACGGGGAGUGGAGUGUGUGGUGUGAUAAGGAACGCUGAAAACAGCCUCCCGAGAAUGCGGUUUGAGUGCUUUUACCAGGCCACAGGUGUCUCAUGACCCGACCUCAAAAAGGCCAUCUAGUGGAUGUUUGUGGUCUAACAAGCCCUUUCAAUGAAUACUUGGCGGACAGAUGCUGGGGCGGAGUCUCUUAGAAGAGCUGCCCCCGGCCCCCCUCAGCUGGAUUUGUCUGAGAACUCAUUCUUGGCGUUCACUGCAAGCUAUAAGCUCUGCGAUGGGCCCUGAAAAAAAAAAAUCGAUACUACGAUGACUCUCAUAUGUAUUUCUUCAGCCCAGAUCCAGACCUUUGUCUACUCAGCUUCUCCACGUGGAUACCUAAUAGGCAUCUCAAAUUUAAAUAUCCAAAACCAAACUCCUGACAUUAAACACAAGAAGCAAGAAAUAUGAACAUAUUUUCUGAUUCCACUAAUAUAAAAGUACAUAACAGUCAA

Taxonomic tree

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Publications