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MIR376C: MIR376C is a microRNA that undergoes rapid turnover, and its abundance and function are highly dependent on the continued transcription and processing of pri-MIR376C [PMC7486624]. The expression of MIR376C leads to an increase in the repression of α1 and γ2 translation, resulting in a reduction in the number of functional synapses at dendritic inhibitory synapses [PMC7486624]. This reduction is manifested by a decrease in the total number of functional synapses [PMC7486624]. The findings suggest that MIR376C plays a crucial role in regulating GABAARs at dendritic inhibitory synapses, potentially impacting synaptic transmission and neuronal excitability [PMC7486624]. Further research is needed to fully understand the mechanisms by which MIR376C influences GABAARs and its implications for neuronal function.
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