MIR1179: MIR1179 is a microRNA (miRNA) that has been identified as a novel locus associated with thyroid-stimulating hormone (TSH) regulation [PMC3567175]. It was found to have a significant association with TSH levels (P = 2.89×10−10) [PMC3567175]. The TSH-elevating allele of MIR1179 was associated with decreasing levels of free thyroxine (FT4) [PMC3567175]. MIR1179 is expressed in various tissues, including the thyroid, brain, and blood [PMC3567175]. The exact biological mechanisms and specific genes involved in the regulation of TSH by MIR1179 are not yet fully understood and require further investigation [PMC3567175]. MIR1179 has also been implicated in other biological processes. It has been shown to interact with hsa_circ_0000652 and OX40L mRNA, as demonstrated by the enrichment of these targets using biotin-labeled hsa-miR-1179 probes [PMC8716807]. Additionally, MIR1179 has been found to be up-regulated in non-functioning adenomas due to lower methylation rates, along with other genes such as CACNA2D4, GRIA2, miR4774, and LINC01351 [PMC7652879]. Furthermore, TargetScan analysis has validated biological targets for MIR1179 [PMC8572446]. In conclusion, MIR1179 is a miRNA that plays a role in TSH regulation and is expressed in various tissues. Its exact mechanisms of action and specific gene targets require further investigation. Additionally, it has been implicated in other biological processes such as adenoma development and target mRNA interactions.