hsa-mir-1279: Hsa-mir-1279 is a microRNA that is predicted to be complementary to the position 648 to 654 of the 3'UTR LYZ region [PMC3448685]. The hsa-mir-1279 rs1463335 proxy, specifically the rs998022, is associated with CTS [PMC3448685]. Hsa-mir-1279 rs1463335 is associated with the expression of LYZ and several other genes, both in cis and in trans [PMC3448685]. The lack of strong correlation between the expression of these genes suggests that they could also be targets for hsa-mir-1279, despite not being predicted by current bioinformatics tools [PMC3448685]. The bioinformatics prediction supports LYZ as a target for hsa-mir-1279 [PMC3448685]. Functional experimental work is needed to further understand the role of hsa-mir-1279 in regulating these genes, particularly TRAF3IP2, which has been identified as a susceptibility locus for psoriasis [PMC3448685]. Positive associations with LYZ and NOD1 and negative associations with other genes are puzzling but could be explained by different regulation mechanisms [PMC3448685]. Hsa-mir-1279 has been found to bind to lncRNA UCA1 and mRNA sequences of PTPN12 orthologues with varying binding energies and complementarity levels [PMC8495997] [PMC3730384]. The binding site between hsa-mir-1279 and ZEB1 mRNA has been identified in different animal species, suggesting conservation across species [PMC3730384].