hsa-mir-764: Interestingly, we also observed three DEmiRNAs, hsa-miR-181a-2-3p, hsa-mir-764 and kshv-miR-K12-6-3p, whose expression in the tissue and blood were entirely opposite [PMC6591379]. This interesting result suggests the need for further investigation into the exact mechanism of hsa-mir-764 in the onset and progression of SCG [PMC6591379]. Previous research has shown that hsa-mir-764 is a biomarker for the diagnosis of hepatocellular carcinoma and lung adenocarcinoma [PMC6591379]. Additionally, hsa-mir-764, along with hsa-miR-181a-2-3p and kshv-miR-K12-6-3p, has been found to be up-regulated in blood but down-regulated in tissues [PMC6591379]. Hsa-mir-764 is located in the second intron of Human serotonin receptor 2C (HTR2C) [PMC2258288]. PCR primers have been used to study hsa-mir-764, including forward primer 5'-GCAGGTGCTCACTTGTCCTCCT' and reverse primer 5'-GCGAGCACAGAATTAATACGAC' [PMC8647233][PMC9254875]. Hsa-mir-764 is one of the top miRNAs with a strong ability to interact with circ-G042080, along with hsa-miR-4268 and hsa-miR3907 [PMC8201884]. It has also been identified as a potential regulator of C2CD4A based on bioinformatics predictions [PMC8520208]. Hsa-mir-764 is among the top 10 differentially expressed miRNAs, along with miRNAs such as hsa-miR31–5p and hsa–miR224–5p [PMC7191371].