rno-mir-3552: Rno-mir-3552 is a novel miRNA candidate that aligns perfectly with rno-mir-3552 and has conserved genomic contexts [PMC3402511]. In a study comparing the MCAO group with the sham group, six miRNAs, including rno-mir-3552, were found to be upregulated, while only rno-mir-194-1 was downregulated [PMC5713304]. Rno-miR-107-5p, rno-miR-196b-5p, and rno-mir-3552 were found to target H2afz, Ptprc, and Srsf2 genes respectively [PMC5713304]. Functional enrichment analysis was conducted to explore the function of targeted mRNAs regulated by rno-mir-3552 [PMC7381948]. In MCAO rat brain tissues, CASP3 was significantly highly expressed while rno-mir-3552 was significantly lowly expressed in MCAO rat blood samples [PMC7381948]. Rno-mir-3552 was found to potentially target Esrrg, Gng7, Nalcn, Clasp2, Faim2 Mast3 and Pip5k1c genes [PMC7381948]. RT-qPCR validation confirmed that rno-mir-3552 was significantly down-regulated in both blood and brain tissue samples of MCAO rats [PMC7381948]. TargetScan miRTarBase miRDB miRanda and miRMap databases were used to predict the corresponding miRNA-mRNA regulatory relationship pairs for targeted mRNAs of rno-mir 3552 [PMC7381948]. Nine differentially expressed miRNAs were identified between MCAO rat blood samples and sham-operated rat blood samples including rnomi-r191b rnomicr743a rnomicr12825p rnomicr3835p rnomir3552 rnomir1075p rnomir1373p rnomir1941 and rnomir429 [PMC7381948].