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hsa-mir-644a: Hsa-mir-644a is a microRNA that has been found to target genes such as CHP1, SLC2A3, and C8orf37 [PMC9738797]. It has been shown to be downregulated in certain conditions, indicating increased expression of its target genes [PMC9781133]. Hsa-mir-644a is also associated with seven HUB nodes, including EGFR and TP53 [PMC5630327]. Lentiviral vectors encoding hsa-mir-644a shRNA have been used in experiments to study its function [PMC5226553]. Site-directed mutagenesis has been used to disrupt the hsa-mir-644a target site in a specific construct [PMC5226553]. In certain conditions, the expression levels of hsa-mir-644a have been found to be normalized compared to control subjects [PMC6719224]. Hsa-mir-644a is one of the differentially expressed miRNAs that have been used for hierarchical clustering analysis [PMC6719224]. In HIV-infected breast milk, hsa-mir-644a has been found to be downregulated compared to uninfected milk samples [PMC7395778].
References:
[PMC9738797]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738797/
[PMC9781133]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781133/
[PMC5630327]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630327/
[PMC5226553]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226553/
[PM6719224]: https://www.ncbi.nlm.nih.gov/pmc/articles/PM6719224/
[PM7395778]: https://www.ncbi.nlm.nih.gov/pmc/articles/PM7395778/
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