Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Brugia malayi (agent of lymphatic filariasis) bma-miR-71 URS000053F275_6279

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

bma-mir-71: Bma-mir-71 is a highly expressed microRNA in the juvenile microfilariae (Mf) stage of Brugia malayi, a parasitic nematode [PMC9861972]. It is one of several microRNAs that are overexpressed in the adult stage, along with members of the miR-2 and miR-36 clusters [PMC9861972]. Bma-mir-71 has been found to target ammonium transport protein and proteins involved in the Lin-12/Notch signaling pathway in B. malayi [PMC9861972]. It also has immunomodulatory properties by downregulating proteins involved in the mTOR pathway [PMC9861972]. In addition to B. malayi, bma-mir-71 has also been detected in other parasitic nematodes such as Onchocerca volvulus [PMC5313568]. The miRCURY LNA Universal RT microRNA PCR system has been used to confirm the presence of bma-mir-71 and other parasitic miRNAs [PMC5313568]. The detection of bma-mir-71, along with ov-miR-71-22nt and ov-miR-71-23nt, was consistently observed across multiple samples using this system [PMC5313568]. Synthetic oligoribonucleotides corresponding to bma-mir-71 have been used for validation purposes [PMC5313568].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences
UGAAAGACAUGGGUAGUGA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 5 other species

  1. Apis mellifera ame-miR-71-5p
  2. Bombyx mori bmo-miR-71-5p
  3. Caenorhabditis briggsae cbr-miR-71
  4. Caenorhabditis elegans mir-71
  5. Nasonia vitripennis (jewel wasp) nvi-miR-71
Publications