hsa-mir-593: Hsa-mir-593 is a microRNA that has been studied in various contexts. In one study, it was found that the abundance of hsa-mir-593 increased more in induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) compared to normal human dermal fibroblasts (NHDFs) [PMC4609408]. The study also observed a decrease in the abundance of hsa-miR-29a and hsa-miR-29b, and an increase in hsa-miR-182 in iPSCs and hESCs [PMC4609408]. In another study, it was reported that elevated levels of hsa-mir-593 were found in exosomes induced by rWNT5A, along with three other microRNAs [PMC4022450]. One of these microRNAs, hsa-mir-455, has been previously associated with various forms of cancer [PMC4022450]. Hsa-mir-593 has also been identified as a potential hub microRNA within a network associated with poor prognosis. The target genes of this network were implicated in the cell cycle [PMC8004706]. Hsa-mir-593 is located within an intron of SND1 (staphylococcal nuclease and tudor domain containing 1), which is a component of RISC (RNA-induced silencing complex) [PMC3675212]. Additionally, it was found that hsa-mir-593 comprises a miR-seed-SNP (single nucleotide polymorphism), specifically rs73721294. However, further validation is needed for this SNP [PMC3675212].