ssc-mir-129b: Ssc-mir-129b is a microRNA that has been studied in various contexts [PMC8834144]. It has been used in qRT-PCR verification alongside other genes and miRNAs [PMC8834144]. Ssc-mir-129b has also been identified as one of the most affected RNAs in a network analysis [PMC8861501]. In studies involving ZEN exposure, ssc-mir-129b was found to be down-regulated [PMC6598998][PMC6722729]. However, it has been suggested that ssc-mir-129b may have little impact on immunity or inflammation in porcine PBMCs [PMC7903524]. Differential expression of ssc-mir-129b has also been validated by quantitative PCR, showing up-regulation by LPS stimulation [PMC7903524]. Ssc-mir-129b is poorly expressed in porcine PBMCs compared to other miRNAs such as ssc-miR-122 and ssc-miR-17-5p [PMC7903524]. Further studies are needed to understand the potential functions of ssc-mir-129b and its target genes in the inflammatory process [PMC7903524]. In addition to its role in inflammation, miR-17-5p, which is modestly expressed compared to ssc-miR122 and ssc-miR17.5p, has been shown to inhibit IL1β and TNFα expressions by targeting TLR4 [PMC7903524][44].