hsa-mir-4525: Hsa-mir-4525 is a miRNA that has been studied in various contexts. It has been found that a variant deletion allele may cause a decreased minimum free energy (MFE) for hsa-mir-4525 [PMC3444488]. In SARS-CoV-2 infected patients, hsa-mir-4525 is upregulated [PMC8890551]. In the Omicron variant, there is a nucleotide insertion that provides a binding site for hsa-mir-4525 [PMC9721271]. In small cell lung cancer (SCLC), hsa-mir-4525 is negatively regulated by lncRNAs and circRNAs [PMC9291301]. Hsa-mir-4525 has also been found to be highly upregulated in certain conditions, such as in a study of DE miRNAs where it showed the highest upregulation [PMC8097233]. In seminal plasma samples from non-azoospermic patients with positive testicular sperm extraction (TESE) results, hsa-mir-4525 was found to be upregulated compared to TESE-negative patients [PMC10051987]. Mechanistic studies have shown that lncRNA FOXP4–AS1 and FOXP4 interact with hsa-mir-4525 to form a ceRNA network [PMC10083663]. Additionally, there are significant interactions between hsa-mir-4525 and various lncRNAs based on validated CLIP experiments [PMC9307901]. References: [PMC3444488] [PMC8890551] [PMC9721271] [PMC9291301] [PMC8097233] [PMC10051987] [PM10083663] [PM9307901]