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bta-mir-144: Bta-mir-144 is a microRNA that has been studied in various contexts. It has been found to be negatively correlated with Ruminococcus 1 and uncultured Cyanobacteria [PMC9378797]. Bta-mir-144, along with other miRNAs, has been positively associated with the blue module [PMC9378797]. In the context of large healthy follicles, bta-mir-144 is upregulated and targets signaling pathways involved in follicular cell proliferation and steroid generation [PMC8316591]. During the transition from day 1–28 postpartum, bta-mir-144 is downregulated [PMC9445238]. Bta-mir-144 has been found to be upregulated in S. aureus infected mammary glands but downregulated in E. coli infected mammary glands, suggesting different roles in mastitis caused by different pathogens [PMC5821052]. Bta-mir-144 has also been predicted to target genes involved in immunity [PMC5821052]. It may serve as a biomarker for mastitis caused by S. aureus and E. coli infections [PMC5821052]. Bta-mir-144 is one of the miRNAs that have been validated for expression changes using RT-qPCR in various tissues such as the hypothalamus, pituitary gland, and mammary gland [PMC9821774]. In bovine growth and atresia follicles, bta-mir-144 is upregulated in large healthy follicles compared to small follicles and plays a role in follicular atresia [PMC10080932]. In mature bovine testis, bta-mir-144 is underexpressed compared to the neonatal group along with other miRNAs such as bta-miR-1185 and bta-miR-431 [PMC7312616].
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