mmu-mir-378b: Mmu-mir-378b is a microRNA that has been studied in various contexts [PMC6963666]. In one study, it was found that mmu-mir-378b decreased in activity in dendritic cells (DCs) after CpG stimulation, while other miRNAs such as mmu-miR-29a and mmu-miR-222 increased [PMC6963666]. In another study, mmu-mir-378b was found to be downregulated in liver tissues treated with CCl4 compared to the control group [PMC4926493]. Real-time quantitative reverse transcriptional polymerase chain reaction (qRT-PCR) was used to validate the downregulation of mmu-mir-378b [PMC4926493]. Additionally, during chlamydia infection and reinfection, the expression of mmu-mir-378b changed over time, being upregulated at week 1 and then downregulated at week 8 [PMC6379932]. The differential expression of mmu-mir-378b during chlamydia infection was associated with increased pathology and migration of eosinophils/neutrophils [PMC6379932]. Furthermore, in another study on chlamydia reinfection, the downregulation of mmu-mir-378b was associated with the formation of new fibrous tissues and other pathological changes [PMC6379932]. Overall, these studies highlight the dynamic expression pattern and potential functional roles of mmu-mir-378b in various biological processes.