bta-mir-449b: Bta-mir-449b is a microRNA that is increased at day 7 of the estrous cycle and was not detected at day 3 [PMC4156418]. It has been found to potentially regulate PYCR1 and DDIT4, which are involved in cancer progression and angiogenesis [PMC6876490]. Bta-mir-449b, along with bta-miR-34c, has been suggested to have critical roles in inducing cell transformation by BPV E5 [PMC6876490]. It has also been predicted that bta-mir-449b could bind to and regulate the expression of DDIT4 [PMC6876490]. Bta-mir-449b is one of the six down-regulated miRNAs, along with bta-miR-34c, bta-miR-122, bta-miR-195, bta-miR-2425-5p, and bta-miR-2428-3p [PMC6876490]. PYCR1 is a common target of bta-mir-449b along with other miRNAs such as bta-miR34c [PMC6876490]. DDIT4 is also a target shared by both bta-mir449b and bta-miRNA34c [PMC6876490]. BtmammiRNA143 could not be amplified by Taqman probes in this study [PMC6876490]. BtmammiRNA449b shares four targets with btammiRNA34c: ACAD10, DDIT4, PYCR1, and CLDN2 [PMC6876490]. Additionally, three SNPs were found in the seed regions of three different microRNAs including btammiRNA44b in QTL regions associated with protein content and yield [PMC8486775]. Bta-mir-449b is one of the up-regulated miRNAs in the study [PMC4617749]. It has also been identified as a potential target of hub miRNAs in the context of IRAK1 [PMC8433134].