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hsa-mir-4286: Hsa-mir-4286 is a microRNA that has been studied in relation to the Influenza A H1N1 virus [PMC3521223]. In a population of more than a thousand sequences of segment 5, the binding positions 1161, 65, and 1190 of hsa-mir-4286 were found to be highly conserved [PMC3521223]. The target prediction algorithms identified 94 targets for hsa-mir-4286 [PMC5179095]. Inhibition of hsa-mir-4286 using an anti-miRNA inhibitor resulted in changes in cellular function [PMC5179095]. Hsa-mir-4286 is one of several microRNAs that may regulate four single nucleotide polymorphisms (SNPs) [PMC5899355]. In placenta samples from patients with preeclampsia (PE) and intrauterine growth restriction (IUGR), the expression of hsa-mir-4286 was found to be downregulated, suggesting its involvement in the regulation of signaling pathways in placental tissue [PMC8073204]. Additionally, hsa-mir-4286 was found to be differentially expressed in HRT-18 and Caco-2 cell lines using microarray analyses [PMC5187811].
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