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mmu-mir-3473a: Mmu-mir-3473a is a microRNA that has been found to be upregulated in various studies. It is a type of microRNA that has been implicated in different biological processes. In one study, the upregulation of mmu-mir-3473a was confirmed through qRT-PCR validation assay [PMC6995328]. Another study identified mmu-mir-3473a as one of the differentially expressed miRNAs in RAW264.7 cells infected with B. melitensis [PMC6995328]. Furthermore, mmu-mir-3473a was found to be upregulated in the brains of scrapie-infected mouse models [PMC5148024]. It was also identified as a potential regulator of flotillin 2 (Flot-2) gene expression [PMC5148024]. In addition, mmu-mir-3473a was found to colocalize with Rora in cardiac fibroblasts (CFBs) and may act as a regulator of Rora expression [PMC8825596]. The downregulation of Rora and the upregulation of mmu-mir-3473a were observed in CFBs treated with Ang II [PMC8825596]. Furthermore, mmu-mir-3473a and mmu-miR-1983 were identified as master regulators of heart development through miRNA-seq analysis [PMC8825596]. The interaction between mmu-mir-3473a and Rora was confirmed through FISH experiments conducted in mouse CFBs [PMC8825596].
References:
[PMC6830910]
[PMC6995328]
[PMC5148024]
[PMC8825596]
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