hsa-mir-23c: As Figure 3B shows, among all the upstream miRNAs, hsa-miR-22-3p was negatively correlated with PCGF1, and hsa-mir-23c was positively correlated with PCGF1 in LIHC [PMC9469147]. In addition, these predicted miRNAs were previously reported that hsa-let-7b-5p, hsa-let-7c-5p and hsa-let-7i-5p were up-regulated and hsa-mir-23c and hsa-miR-182-5p were down-regulated in NOA [PMC7041731]. The correlation between lncRNAs and hsa-miR-101-3p, hsa-miR-125b-5p and hsa-mir-23c was detected by the ENCORI database, and the results showed that 14 lncRNAs were significantly associated with hsa-miR-101-3p and GLS, 9 lncRNAs were significantly associated with hsa-miR-125b-5p and CDKN2A, 10 lncRNAs were significantly associated with hsa-miR-125b-5p and GLS, 4 lncRNAs were significantly associated with hsa-miR-125b-5p and PDHA1, and 12 lncRNAs were significantly associated with hsa-mir-23c and GLS [PMC9986498]. A direct comparison of miRNA levels between the two neoplasias (by miRanalyzer tool Differential expression analysis) showed 13 upregulated miRNAs (hsa-miR-1292-5p, hsa-140-5p, hsa-miR-184, hsa-miR-1908, hsa-miR-23b-5p, has-miR-3198, hsa-miR-323b-3p, hsa-miR-331-3p, hsa-miR-409-5p, hsa-miR-4683, hsa-miR-4707-3p, hsa-miR-505-5p, hsa-miR-5706), and 5 down-regulated miRNAs (hsa-miR-106a-5p, hsa-miR-200b-3p, hsa-miR-216b, hsa-mir-23c, hsa-miR-29b-3p) in MPM compared to AD [PMC4464514]. As shown in Figure 2A, the expression levels of hsa-miR-323b-3p, hsa-miR-323b-3p, hsa-miR-371a-5p, hsa-miR-708-3p, hsa-miR-6852-5p, hsa-miR-767-5p, hsa-miR-382-5p, and hsa-miR-514a-3p were significantly upregulated in SW620-Smad4 cells, whereas, as shown in Figure 2B, hsa-miR-1289, hsa-miR-1537-5p, hsa-mir-23c, hsa-miR-3199, hsa-miR-3619-5p, hsa-miR-3657, hsa-miR-548u, hsa-miR-5699-5p, and hsa-miR-874-5p were downregulated [PMC6235008].