Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
ssc-miR-34c: Ssc-mir-34c is a microRNA that has been found to be upregulated in various studies [PMC8367414][PMC7531090][PMC6090871][PMC10000162][PMC9220968][PMC7724732][PMC7247556][PMC5909910]. It is one of the most abundant miRNAs [PMC7724732] and has been implicated in the regulation of male sexual function [PMC7531090]. Ssc-mir-34c has been found to target genes such as phospholipase C beta 1 (PLCĪ²1) and serine/threonine/tyrosine interacting protein (STYX) involved in signaling pathways such as GnRH, Wnt, and MAPK [PMC7531090]. It has also been shown to target genes involved in the p53 signaling pathway, including cyclin D2 (CCND2), phosphatase and tensin homolog (PTEN), and cyclin B1 (CCNB1) [PMC7531090]. Ssc-mir-34c has been implicated in viral pathogenicity as it can bind to the 3' UTR of the CHX1401 virus genome [PMC10000162]. Additionally, it forms a ceRNA relationship with ssc-miR-9851-3p and ssc-miR-34c, regulating the corresponding NR4A2 gene [PMC9220968]. Ssc-mir-34c expression is affected by ischemia/reperfusion, but can be modulated by ischemic preconditioning (IPC) and ischemic postconditioning (IPoC) [ PMC7247556]. Overall, ssc-mir-34c plays a role in various biological processes through its regulation of target genes.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset