hsa-mir-548c: Hsa-mir-548c is a miRNA that has been associated with longer survival times in patients with STAD (stomach adenocarcinoma) [PMC6448084]. It has been confirmed to downregulate CAMK1D, a protective miRNA [PMC6448084]. On the other hand, hsa-mir-1255a, hsa-mir-3687, and hsa-mir-9-3 have been associated with shorter survival times in STAD patients [PMC6448084]. These miRNAs can be used as risk factors or protective indicators with prognostic ability in STAD patients [PMC6448084]. Patients with high levels of hsa-mir-1255a, hsa-mir-3687, and hsa-mir-9-3 have high risk scores and shorter survival times, while those with high levels of hsa-mir-548c and hsa-mir-7-2 have low risk scores and longer survival times [PMC6448084]. Hsa-mir-548c plays a complex and important role in the development of STAD [PMC6448084]. It is part of a 5-miRNA signature (hsa-mir1255a, hsa-miR3687, hsa-miR9.3, hsa mir548c and has mir 7.2) that can independently predict the survival time of STAD patients [PMC6448084]. Elevated expression levels of HSA mir 1255a, HSA mir 3687, and HSA mir 9.3 are associated with poor prognosis [PMC6448084]. HSA-MIR-548C is also upregulated in esophageal cancer tissues compared to normal esophageal tissues [PMC8325912]. It is part of a microRNA prognostic panel for gastric cancer patients [PMC7692123]. The relationship between hsa-mir-548c and CCNB1 is unknown [PMC9852745]. It has been found to be upregulated or downregulated in various cancers [PMC3794036]. The functional studies in endometrial, ovarian, and liver cancer suggest that decreased hsa-mir-548c expression promotes cell migration and invasion potentially by silencing the EMT marker TWIST [PMC5823652].