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hsa-mir-4785: Hsa-mir-4785 is a microRNA that has been studied in various contexts. In the presence of LPS, MlEVs were found to partially restore miRNA expression, including the downregulation of hsa-mir-4785 [PMC9898544]. Hsa-mir-4785 is also one of the dysregulated miRNAs common to all four pairwise comparisons in a study [PMC7880712]. It has been observed to be downregulated in human nasal epithelial cells treated with the TLR3 ligand poly(I:C) [PMC5223123]. Hsa-mir-4785 has also been identified as one of the candidates with an ovarian-predominant expression profile in a QPCR analysis [PMC5223123]. Additionally, hsa-mir-4785 is one of the miRNAs that had never been reported as ovarian-predominant in any vertebrate species [PMC5223123]. The ovarian-predominant expression is particularly strict for hsa-mir-4785, along with mmu-miR-6352, dre-miR-729, and hsa-miR-4653 [PMC5223123]. Overall, hsa-mir-4785 has been found to be dysregulated and downregulated in various contexts and may play a role in ovarian function.
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