bmo-let-7: Bmo-let-7 is a microRNA that is expressed in various tissues of the silkworm, Bombyx mori, and is regulated by ecdysone, a hormone involved in insect development [PMC4222307]. The expression of bmo-let-7 is influenced by the concentration of ecdysone, with higher levels of ecdysone leading to down-regulation of bmo-let-7 [PMC1976426]. The expression profile of bmo-let-7 varies during the development of the silkworm, with higher expression levels observed during certain molting stages [PMC1976426]. The expression of bmo-let-7 is induced by a pulse of ecdysone and may be involved in processes such as cell proliferation, histogenesis, histolysis, organogenesis, and apoptosis [PMC1976426]. Bmo-let-7 is highly expressed in pupae and its expression may be induced by ecdysone in various tissues [PMC1976426]. The expression profile of bmo-let-7 differs among tissues and developmental stages [PMC1976426]. Bmo-let-7 has been identified as a member of the let-7 family in Bombyx mori and its expression has been profiled using Northern blotting [PMC1976426]. Bmo-bantam and bmo-miR31 are other highly abundant miRNAs identified in Bombyx mori [PMC3699532]. A miRNA sponge construct targeting bmo let 7 has been shown to induce developmental arrest by targeting FTZ-F1 and Eip74EF (E74) in the ecdysone pathway [PMC5689003].